Abou El Ella DA - Search Results

1

Amido/ureidosubstituted benzenesulfonamides-isatin conjugates as low nanomolar/subnanomolar inhibitors of the tumor-associated carbonic anhydrase isoform XII.

Eldehna WM, Fares M, Ceruso M, Ghabbour HA, Abou-Seri SM, Abdel-Aziz HA, Abou El Ella DA, Supuran CT. Eldehna WM, et al. Among authors: abou seri sm, abou el ella da. Eur J Med Chem. 2016 Mar 3;110:259-66. doi: 10.1016/j.ejmech.2016.01.030. Epub 2016 Jan 20. Eur J Med Chem. 2016. PMID: 26840366

2

Design and synthesis of new tetrazolyl- and carboxy-biphenylylmethyl-quinazolin-4-one derivatives as angiotensin II AT1 receptor antagonists.

Ismail MA, Barker S, Abou el-Ella DA, Abouzid KA, Toubar RA, Todd MH. Ismail MA, et al. Among authors: abou el ella da. J Med Chem. 2006 Mar 9;49(5):1526-35. doi: 10.1021/jm050232e. J Med Chem. 2006. PMID: 16509571

3

Molecular modeling study and synthesis of novel pyrrolo[2,3-d]pyrimidines and pyrrolotriazolopyrimidines of expected antitumor and radioprotective activities.

Abou El Ella DA, Ghorab MM, Noaman E, Heiba HI, Khalil AI. Abou El Ella DA, et al. Bioorg Med Chem. 2008 Mar 1;16(5):2391-402. doi: 10.1016/j.bmc.2007.11.072. Epub 2007 Nov 29. Bioorg Med Chem. 2008. PMID: 18086527

4

ACE inhibitors hypothesis generation for selective design, synthesis and biological evaluation of 3-mercapto-2-methyl-propanoyl-pyrrolidine-3-imine derivatives as antihypertensive agents.

Ismail MA, Nabil Aboul-Enein M, Abouzid KA, Abou El Ella DA, Ismail NS. Ismail MA, et al. Among authors: abou el ella da. Bioorg Med Chem. 2009 May 15;17(10):3739-46. doi: 10.1016/j.bmc.2009.03.008. Epub 2009 Mar 10. Bioorg Med Chem. 2009. PMID: 19403313

5

Discovery of colon tumor cell growth inhibitory agents through a combinatorial approach.

Abadi AH, Abouel-Ella DA, Lehmann J, Tinsley HN, Gary BD, Piazza GA, Abdel-Fattah MA. Abadi AH, et al. Eur J Med Chem. 2010 Jan;45(1):90-7. doi: 10.1016/j.ejmech.2009.09.029. Epub 2009 Sep 20. Eur J Med Chem. 2010. PMID: 19836860 Free PMC article.

6

Molecular modeling study and synthesis of quinazolinone-arylpiperazine derivatives as α1-adrenoreceptor antagonists.

Abou-Seri SM, Abouzid K, Abou El Ella DA. Abou-Seri SM, et al. Among authors: abou el ella da. Eur J Med Chem. 2011 Feb;46(2):647-58. doi: 10.1016/j.ejmech.2010.11.045. Epub 2010 Dec 8. Eur J Med Chem. 2011. PMID: 21193252

7

Integrated structure-based activity prediction model of benzothiadiazines on various genotypes of HCV NS5b polymerase (1a, 1b and 4) and its application in the discovery of new derivatives.

Ismail MA, Abou El Ella DA, Abouzid KA, Mahmoud AH. Ismail MA, et al. Among authors: abou el ella da. Bioorg Med Chem. 2012 Apr 1;20(7):2455-78. doi: 10.1016/j.bmc.2012.01.031. Epub 2012 Jan 28. Bioorg Med Chem. 2012. PMID: 22386565

8

A highly selective structure-based virtual screening model of Palm I allosteric inhibitors of HCV Ns5b polymerase enzyme and its application in the discovery and optimization of new analogues.

Mahmoud AH, Abou El Ella DA, Ismail MA, Abouzid KA. Mahmoud AH, et al. Among authors: abou el ella da. Eur J Med Chem. 2012 Nov;57:468-82. doi: 10.1016/j.ejmech.2012.04.016. Epub 2012 Apr 25. Eur J Med Chem. 2012. PMID: 22824204

9

Analogs design, synthesis and biological evaluation of peptidomimetics with potential anti-HCV activity.

Lasheen DS, Ismail MA, Abou El Ella DA, Ismail NS, Eid S, Vleck S, Glenn JS, Watts AG, Abouzid KA. Lasheen DS, et al. Among authors: abou el ella da. Bioorg Med Chem. 2013 May 15;21(10):2742-55. doi: 10.1016/j.bmc.2013.03.017. Epub 2013 Mar 24. Bioorg Med Chem. 2013. PMID: 23583031

10

Molecular design and synthesis of HCV inhibitors based on thiazolone scaffold.

Al-Ansary GH, Ismail MA, Abou El Ella DA, Eid S, Abouzid KA. Al-Ansary GH, et al. Among authors: abou el ella da. Eur J Med Chem. 2013 Oct;68:19-32. doi: 10.1016/j.ejmech.2013.07.006. Epub 2013 Jul 24. Eur J Med Chem. 2013. PMID: 23933047

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