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Omics for prediction of environmental health effects: Blood leukocyte-based cross-omic profiling reliably predicts diseases associated with tobacco smoking.
Georgiadis P, Hebels DG, Valavanis I, Liampa I, Bergdahl IA, Johansson A, Palli D, Chadeau-Hyam M, Chatziioannou A, Jennen DG, Krauskopf J, Jetten MJ, Kleinjans JC, Vineis P, Kyrtopoulos SA; EnviroGenomarkers consortium. Georgiadis P, et al. Among authors: kleinjans jc. Sci Rep. 2016 Feb 3;6:20544. doi: 10.1038/srep20544. Sci Rep. 2016. PMID: 26837704 Free PMC article.
Biological marks of early-life socioeconomic experience is detected in the adult inflammatory transcriptome.
Castagné R, Kelly-Irving M, Campanella G, Guida F, Krogh V, Palli D, Panico S, Sacerdote C, Tumino R, Kleinjans J, de Kok T, Kyrtopoulos SA, Lang T, Stringhini S, Vermeulen R, Vineis P, Delpierre C, Chadeau-Hyam M. Castagné R, et al. Sci Rep. 2016 Dec 9;6:38705. doi: 10.1038/srep38705. Sci Rep. 2016. PMID: 27934951 Free PMC article. Clinical Trial.
Blood-based omic profiling supports female susceptibility to tobacco smoke-induced cardiovascular diseases.
Chatziioannou A, Georgiadis P, Hebels DG, Liampa I, Valavanis I, Bergdahl IA, Johansson A, Palli D, Chadeau-Hyam M, Siskos AP, Keun H, Botsivali M, de Kok TM, Pérez AE, Kleinjans JC, Vineis P, Kyrtopoulos SA; EnviroGenomarkers project consortium. Chatziioannou A, et al. Among authors: kleinjans jc. Sci Rep. 2017 Feb 22;7:42870. doi: 10.1038/srep42870. Sci Rep. 2017. PMID: 28225026 Free PMC article.
Evolving DNA methylation and gene expression markers of B-cell chronic lymphocytic leukemia are present in pre-diagnostic blood samples more than 10 years prior to diagnosis.
Georgiadis P, Liampa I, Hebels DG, Krauskopf J, Chatziioannou A, Valavanis I, de Kok TMCM, Kleinjans JCS, Bergdahl IA, Melin B, Spaeth F, Palli D, Vermeulen RCH, Vlaanderen J, Chadeau-Hyam M, Vineis P, Kyrtopoulos SA; EnviroGenomarkers consortium. Georgiadis P, et al. BMC Genomics. 2017 Sep 13;18(1):728. doi: 10.1186/s12864-017-4117-4. BMC Genomics. 2017. PMID: 28903739 Free PMC article.
Prediagnostic transcriptomic markers of Chronic lymphocytic leukemia reveal perturbations 10 years before diagnosis.
Chadeau-Hyam M, Vermeulen RC, Hebels DG, Castagné R, Campanella G, Portengen L, Kelly RS, Bergdahl IA, Melin B, Hallmans G, Palli D, Krogh V, Tumino R, Sacerdote C, Panico S, de Kok TM, Smith MT, Kleinjans JC, Vineis P, Kyrtopoulos SA; EnviroGenoMarkers project consortium. Chadeau-Hyam M, et al. Among authors: kleinjans jc. Ann Oncol. 2014 May;25(5):1065-72. doi: 10.1093/annonc/mdu056. Epub 2014 Feb 20. Ann Oncol. 2014. PMID: 24558024 Free PMC article.
The human circulating miRNome reflects multiple organ disease risks in association with short-term exposure to traffic-related air pollution.
Krauskopf J, Caiment F, van Veldhoven K, Chadeau-Hyam M, Sinharay R, Chung KF, Cullinan P, Collins P, Barratt B, Kelly FJ, Vermeulen R, Vineis P, de Kok TM, Kleinjans JC. Krauskopf J, et al. Among authors: kleinjans jc. Environ Int. 2018 Apr;113:26-34. doi: 10.1016/j.envint.2018.01.014. Epub 2018 Jan 28. Environ Int. 2018. PMID: 29421404 Free article.
DNA methylation and exposure to ambient air pollution in two prospective cohorts.
Plusquin M, Guida F, Polidoro S, Vermeulen R, Raaschou-Nielsen O, Campanella G, Hoek G, Kyrtopoulos SA, Georgiadis P, Naccarati A, Sacerdote C, Krogh V, Bas Bueno-de-Mesquita H, Monique Verschuren WM, Sayols-Baixeras S, Panni T, Peters A, Hebels DGAJ, Kleinjans J, Vineis P, Chadeau-Hyam M. Plusquin M, et al. Environ Int. 2017 Nov;108:127-136. doi: 10.1016/j.envint.2017.08.006. Epub 2017 Aug 24. Environ Int. 2017. PMID: 28843141 Free PMC article.
371 results