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Exercise-induced mitochondrial p53 repairs mtDNA mutations in mutator mice.
Safdar A, Khrapko K, Flynn JM, Saleem A, De Lisio M, Johnston AP, Kratysberg Y, Samjoo IA, Kitaoka Y, Ogborn DI, Little JP, Raha S, Parise G, Akhtar M, Hettinga BP, Rowe GC, Arany Z, Prolla TA, Tarnopolsky MA. Safdar A, et al. Among authors: little jp. Skelet Muscle. 2016 Jan 31;6:7. doi: 10.1186/s13395-016-0075-9. eCollection 2016. Skelet Muscle. 2016. Retraction in: Skelet Muscle. 2021 Mar 30;11(1):8. doi: 10.1186/s13395-021-00264-7 PMID: 26834962 Free PMC article. Retracted.
Exercise increases mitochondrial PGC-1alpha content and promotes nuclear-mitochondrial cross-talk to coordinate mitochondrial biogenesis.
Safdar A, Little JP, Stokl AJ, Hettinga BP, Akhtar M, Tarnopolsky MA. Safdar A, et al. Among authors: little jp. J Biol Chem. 2011 Mar 25;286(12):10605-17. doi: 10.1074/jbc.M110.211466. Epub 2011 Jan 18. J Biol Chem. 2011. Retraction in: J Biol Chem. 2020 Dec 18;295(51):17888. doi: 10.1074/jbc.W120.016876 PMID: 21245132 Free PMC article. Retracted.
Endurance exercise rescues progeroid aging and induces systemic mitochondrial rejuvenation in mtDNA mutator mice.
Safdar A, Bourgeois JM, Ogborn DI, Little JP, Hettinga BP, Akhtar M, Thompson JE, Melov S, Mocellin NJ, Kujoth GC, Prolla TA, Tarnopolsky MA. Safdar A, et al. Among authors: little jp. Proc Natl Acad Sci U S A. 2011 Mar 8;108(10):4135-40. doi: 10.1073/pnas.1019581108. Epub 2011 Feb 22. Proc Natl Acad Sci U S A. 2011. PMID: 21368114 Free PMC article.
276 results