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THSD1 preserves vascular integrity and protects against intraplaque haemorrhaging in ApoE-/- mice.
Haasdijk RA, Den Dekker WK, Cheng C, Tempel D, Szulcek R, Bos FL, Hermkens DM, Chrifi I, Brandt MM, Van Dijk C, Xu YJ, Van De Kamp EH, Blonden LA, Van Bezu J, Sluimer JC, Biessen EA, Van Nieuw Amerongen GP, Duckers HJ. Haasdijk RA, et al. Among authors: van bezu j, van dijk c, van de kamp eh, van nieuw amerongen gp. Cardiovasc Res. 2016 May 1;110(1):129-39. doi: 10.1093/cvr/cvw015. Epub 2016 Jan 27. Cardiovasc Res. 2016. PMID: 26822228
Localized RhoA GTPase activity regulates dynamics of endothelial monolayer integrity.
Szulcek R, Beckers CM, Hodzic J, de Wit J, Chen Z, Grob T, Musters RJ, Minshall RD, van Hinsbergh VW, van Nieuw Amerongen GP. Szulcek R, et al. Among authors: van hinsbergh vw, van nieuw amerongen gp. Cardiovasc Res. 2013 Aug 1;99(3):471-82. doi: 10.1093/cvr/cvt075. Epub 2013 Mar 27. Cardiovasc Res. 2013. PMID: 23536606 Free PMC article.
RhoA, RhoB and RhoC differentially regulate endothelial barrier function.
Pronk MCA, van Bezu JSM, van Nieuw Amerongen GP, van Hinsbergh VWM, Hordijk PL. Pronk MCA, et al. Among authors: van nieuw amerongen gp. Small GTPases. 2019 Nov;10(6):466-484. doi: 10.1080/21541248.2017.1339767. Epub 2017 Sep 26. Small GTPases. 2019. PMID: 28949796 Free PMC article.
Nintedanib improves cardiac fibrosis but leaves pulmonary vascular remodelling unaltered in experimental pulmonary hypertension.
Rol N, de Raaf MA, Sun XQ, Kuiper VP, da Silva Gonçalves Bos D, Happé C, Kurakula K, Dickhoff C, Thuillet R, Tu L, Guignabert C, Schalij I, Lodder K, Pan X, Herrmann FE, van Nieuw Amerongen GP, Koolwijk P, Vonk-Noordegraaf A, de Man FS, Wollin L, Goumans MJ, Szulcek R, Bogaard HJ. Rol N, et al. Among authors: van nieuw amerongen gp. Cardiovasc Res. 2019 Feb 1;115(2):432-439. doi: 10.1093/cvr/cvy186. Cardiovasc Res. 2019. PMID: 30032282
Effective treatment of edema and endothelial barrier dysfunction with imatinib.
Aman J, van Bezu J, Damanafshan A, Huveneers S, Eringa EC, Vogel SM, Groeneveld AB, Vonk Noordegraaf A, van Hinsbergh VW, van Nieuw Amerongen GP. Aman J, et al. Among authors: van bezu j, van hinsbergh vw, van nieuw amerongen gp. Circulation. 2012 Dec 4;126(23):2728-38. doi: 10.1161/CIRCULATIONAHA.112.134304. Epub 2012 Oct 25. Circulation. 2012. PMID: 23099479
Depletion of Arg/Abl2 improves endothelial cell adhesion and prevents vascular leak during inflammation.
Amado-Azevedo J, van Stalborch AD, Valent ET, Nawaz K, van Bezu J, Eringa EC, Hoevenaars FPM, De Cuyper IM, Hordijk PL, van Hinsbergh VWM, van Nieuw Amerongen GP, Aman J, Margadant C. Amado-Azevedo J, et al. Among authors: van nieuw amerongen gp. Angiogenesis. 2021 Aug;24(3):677-693. doi: 10.1007/s10456-021-09781-x. Epub 2021 Mar 26. Angiogenesis. 2021. PMID: 33770321 Free PMC article.
87 results