Lagae L - Search Results

1

Serotonergic Modulation as Effective Treatment for Dravet Syndrome in a Zebrafish Mutant Model.

Sourbron J, Schneider H, Kecskés A, Liu Y, Buening EM, Lagae L, Smolders I, de Witte P. Sourbron J, et al. Among authors: lagae l. ACS Chem Neurosci. 2016 May 18;7(5):588-98. doi: 10.1021/acschemneuro.5b00342. Epub 2016 Feb 17. ACS Chem Neurosci. 2016. PMID: 26822114

2

Successful use of fenfluramine as an add-on treatment for Dravet syndrome.

Ceulemans B, Boel M, Leyssens K, Van Rossem C, Neels P, Jorens PG, Lagae L. Ceulemans B, et al. Among authors: lagae l. Epilepsia. 2012 Jul;53(7):1131-9. doi: 10.1111/j.1528-1167.2012.03495.x. Epub 2012 May 3. Epilepsia. 2012. PMID: 22554283 Free article.

3

Pharmacological characterization of an antisense knockdown zebrafish model of Dravet syndrome: inhibition of epileptic seizures by the serotonin agonist fenfluramine.

Zhang Y, Kecskés A, Copmans D, Langlois M, Crawford AD, Ceulemans B, Lagae L, de Witte PA, Esguerra CV. Zhang Y, et al. Among authors: lagae l. PLoS One. 2015 May 12;10(5):e0125898. doi: 10.1371/journal.pone.0125898. eCollection 2015. PLoS One. 2015. PMID: 25965391 Free PMC article.

4

Gain-of-function FHF1 mutation causes early-onset epileptic encephalopathy with cerebellar atrophy.

Siekierska A, Isrie M, Liu Y, Scheldeman C, Vanthillo N, Lagae L, de Witte PA, Van Esch H, Goldfarb M, Buyse GM. Siekierska A, et al. Among authors: lagae l. Neurology. 2016 Jun 7;86(23):2162-70. doi: 10.1212/WNL.0000000000002752. Epub 2016 May 4. Neurology. 2016. PMID: 27164707 Free PMC article.

5

Five-year extended follow-up status of 10 patients with Dravet syndrome treated with fenfluramine.

Ceulemans B, Schoonjans AS, Marchau F, Paelinck BP, Lagae L. Ceulemans B, et al. Among authors: lagae l. Epilepsia. 2016 Jul;57(7):e129-34. doi: 10.1111/epi.13407. Epub 2016 May 20. Epilepsia. 2016. PMID: 27197941 Free article.

6

Vagus Nerve Stimulation in children: A focus on intellectual disability.

Sourbron J, Klinkenberg S, Kessels A, Schelhaas HJ, Lagae L, Majoie M. Sourbron J, et al. Among authors: lagae l. Eur J Paediatr Neurol. 2017 May;21(3):427-440. doi: 10.1016/j.ejpn.2017.01.011. Epub 2017 Jan 30. Eur J Paediatr Neurol. 2017. PMID: 28188025 Review.

7

Serotonergic modulation as a pharmacological modality in the treatment of Dravet syndrome.

de Witte P, Lagae L. de Witte P, et al. Among authors: lagae l. Brain. 2017 Jun 1;140(6):e35. doi: 10.1093/brain/awx090. Brain. 2017. PMID: 28402511 Free PMC article. No abstract available.

8

Pharmacological Analysis of the Anti-epileptic Mechanisms of Fenfluramine in scn1a Mutant Zebrafish.

Sourbron J, Smolders I, de Witte P, Lagae L. Sourbron J, et al. Among authors: lagae l. Front Pharmacol. 2017 Apr 6;8:191. doi: 10.3389/fphar.2017.00191. eCollection 2017. Front Pharmacol. 2017. PMID: 28428755 Free PMC article.

9

Scheldeman C, Mills JD, Siekierska A, Serra I, Copmans D, Iyer AM, Whalley BJ, Maes J, Jansen AC, Lagae L, Aronica E, de Witte PAM. Scheldeman C, et al. Among authors: lagae l. Neurobiol Dis. 2017 Dec;108:225-237. doi: 10.1016/j.nbd.2017.09.004. Epub 2017 Sep 6. Neurobiol Dis. 2017. PMID: 28888969

10

Drug repurposing for Dravet syndrome in scn1Lab^-/- mutant zebrafish.

Sourbron J, Partoens M, Scheldeman C, Zhang Y, Lagae L, de Witte P. Sourbron J, et al. Among authors: lagae l. Epilepsia. 2019 Feb;60(2):e8-e13. doi: 10.1111/epi.14647. Epub 2019 Jan 20. Epilepsia. 2019. PMID: 30663052 Free PMC article.

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