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Human coronavirus OC43-elicited CD4+ T cells protect against SARS-CoV-2 in HLA transgenic mice.
Dos Santos Alves RP, Timis J, Miller R, Valentine K, Pinto PBA, Gonzalez A, Regla-Nava JA, Maule E, Nguyen MN, Shafee N, Landeras-Bueno S, Olmedillas E, Laffey B, Dobaczewska K, Mikulski Z, McArdle S, Leist SR, Kim K, Baric RS, Ollmann Saphire E, Elong Ngono A, Shresta S. Dos Santos Alves RP, et al. Among authors: leist sr. Nat Commun. 2024 Jan 26;15(1):787. doi: 10.1038/s41467-024-45043-2. Nat Commun. 2024. PMID: 38278784 Free PMC article.
Clonal replacement sustains long-lived germinal centers primed by respiratory viruses.
de Carvalho RVH, Ersching J, Barbulescu A, Hobbs A, Castro TBR, Mesin L, Jacobsen JT, Phillips BK, Hoffmann HH, Parsa R, Canesso MCC, Nowosad CR, Feng A, Leist SR, Baric RS, Yang E, Utz PJ, Victora GD. de Carvalho RVH, et al. Among authors: leist sr. Cell. 2023 Jan 5;186(1):131-146.e13. doi: 10.1016/j.cell.2022.11.031. Epub 2022 Dec 23. Cell. 2023. PMID: 36565697 Free PMC article.
Nanoparticle display of prefusion coronavirus spike elicits S1-focused cross-reactive antibody response against diverse coronavirus subgenera.
Hutchinson GB, Abiona OM, Ziwawo CT, Werner AP, Ellis D, Tsybovsky Y, Leist SR, Palandjian C, West A, Fritch EJ, Wang N, Wrapp D, Boyoglu-Barnum S, Ueda G, Baker D, Kanekiyo M, McLellan JS, Baric RS, King NP, Graham BS, Corbett-Helaire KS. Hutchinson GB, et al. Among authors: leist sr. Nat Commun. 2023 Oct 4;14(1):6195. doi: 10.1038/s41467-023-41661-4. Nat Commun. 2023. PMID: 37794071 Free PMC article.
A C57BL/6 Mouse model of SARS-CoV-2 infection recapitulates age- and sex-based differences in human COVID-19 disease and recovery.
Davis M, Voss K, Turnbull JB, Gustin AT, Knoll M, Muruato A, Hsiang TY, Dinnon KH 3rd, Leist SR, Nickel K, Baric RS, Ladiges W, Akilesh S, Smith KD, Gale M. Davis M, et al. Among authors: leist sr. Res Sq [Preprint]. 2022 Nov 14:rs.3.rs-2194450. doi: 10.21203/rs.3.rs-2194450/v1. Res Sq. 2022. Update in: Vaccines (Basel). 2022 Dec 25;11(1):47. doi: 10.3390/vaccines11010047 PMID: 36415465 Free PMC article. Updated. Preprint.
A MERS-CoV antibody neutralizes a pre-emerging group 2c bat coronavirus.
Tse LV, Hou YJ, McFadden E, Lee RE, Scobey TD, Leist SR, Martinez DR, Meganck RM, Schäfer A, Yount BL, Mascenik T, Powers JM, Randell SH, Zhang Y, Wang L, Mascola J, McLellan JS, Baric RS. Tse LV, et al. Among authors: leist sr. Sci Transl Med. 2023 Sep 27;15(715):eadg5567. doi: 10.1126/scitranslmed.adg5567. Epub 2023 Sep 27. Sci Transl Med. 2023. PMID: 37756379 Free PMC article.
Broadly neutralizing antibodies against sarbecoviruses generated by immunization of macaques with an AS03-adjuvanted COVID-19 vaccine.
Feng Y, Yuan M, Powers JM, Hu M, Munt JE, Arunachalam PS, Leist SR, Bellusci L, Kim J, Sprouse KR, Adams LE, Sundaramurthy S, Zhu X, Shirreff LM, Mallory ML, Scobey TD, Moreno A, O'Hagan DT, Kleanthous H, Villinger FJ, Veesler D, King NP, Suthar MS, Khurana S, Baric RS, Wilson IA, Pulendran B. Feng Y, et al. Among authors: leist sr. Sci Transl Med. 2023 May 10;15(695):eadg7404. doi: 10.1126/scitranslmed.adg7404. Epub 2023 May 10. Sci Transl Med. 2023. PMID: 37163615 Free PMC article.
Fc mediated pan-sarbecovirus protection after alphavirus vector vaccination.
Adams LE, Leist SR, Dinnon KH, West A, Gully KL, Anderson EJ, Loome JF, Madden EA, Powers JM, Schäfer A, Sarkar S, Castillo IN, Maron JS, McNamara RP, Bertera HL, Zweigert MR, Higgins JS, Hampton BK, Premkumar L, Alter G, Montgomery SA, Baxter VK, Heise MT, Baric RS. Adams LE, et al. Among authors: leist sr. bioRxiv [Preprint]. 2022 Nov 28:2022.11.28.518175. doi: 10.1101/2022.11.28.518175. bioRxiv. 2022. Update in: Cell Rep. 2023 Apr 25;42(4):112326. doi: 10.1016/j.celrep.2023.112326 PMID: 36482964 Free PMC article. Updated. Preprint.
100 results