Largiadèr CR - Search Results

1

Rs895819 in MIR27A improves the predictive value of DPYD variants to identify patients at risk of severe fluoropyrimidine-associated toxicity.

Meulendijks D, Henricks LM, Amstutz U, Froehlich TK, Largiadèr CR, Beijnen JH, de Boer A, Deenen MJ, Cats A, Schellens JH. Meulendijks D, et al. Among authors: largiader cr. Int J Cancer. 2016 Jun 1;138(11):2752-61. doi: 10.1002/ijc.30014. Epub 2016 Feb 19. Int J Cancer. 2016. PMID: 26804235

2

Population transcriptomics of life-history variation in the genus Salmo.

Giger T, Excoffier L, Amstutz U, Day PJ, Champigneulle A, Hansen MM, Kelso J, Largiadèr CR. Giger T, et al. Among authors: largiader cr. Mol Ecol. 2008 Jul;17(13):3095-108. doi: 10.1111/j.1365-294X.2008.03820.x. Epub 2008 Jun 3. Mol Ecol. 2008. PMID: 18522696

3

Hypermethylation of the DPYD promoter region is not a major predictor of severe toxicity in 5-fluorouracil based chemotherapy.

Amstutz U, Farese S, Aebi S, Largiadèr CR. Amstutz U, et al. Among authors: largiader cr. J Exp Clin Cancer Res. 2008 Oct 20;27(1):54. doi: 10.1186/1756-9966-27-54. J Exp Clin Cancer Res. 2008. PMID: 18937829 Free PMC article.

4

Dihydropyrimidine dehydrogenase gene variation and severe 5-fluorouracil toxicity: a haplotype assessment.

Amstutz U, Farese S, Aebi S, Largiadèr CR. Amstutz U, et al. Among authors: largiader cr. Pharmacogenomics. 2009 Jun;10(6):931-44. doi: 10.2217/pgs.09.28. Pharmacogenomics. 2009. PMID: 19530960

5

Sequence capture and next-generation resequencing of multiple tagged nucleic acid samples for mutation screening of urea cycle disorders.

Amstutz U, Andrey-Zürcher G, Suciu D, Jaggi R, Häberle J, Largiadèr CR. Amstutz U, et al. Among authors: largiader cr. Clin Chem. 2011 Jan;57(1):102-11. doi: 10.1373/clinchem.2010.150706. Epub 2010 Nov 10. Clin Chem. 2011. PMID: 21068339 Free article.

6

Dihydropyrimidine dehydrogenase gene as a major predictor of severe 5-fluorouracil toxicity.

Amstutz U, Froehlich TK, Largiadèr CR. Amstutz U, et al. Among authors: largiader cr. Pharmacogenomics. 2011 Sep;12(9):1321-36. doi: 10.2217/pgs.11.72. Pharmacogenomics. 2011. PMID: 21919607 Review.

7

LC-MS/MS method for simultaneous analysis of uracil, 5,6-dihydrouracil, 5-fluorouracil and 5-fluoro-5,6-dihydrouracil in human plasma for therapeutic drug monitoring and toxicity prediction in cancer patients.

Büchel B, Rhyn P, Schürch S, Bühr C, Amstutz U, Largiadèr CR. Büchel B, et al. Among authors: largiader cr. Biomed Chromatogr. 2013 Jan;27(1):7-16. doi: 10.1002/bmc.2741. Epub 2012 Mar 27. Biomed Chromatogr. 2013. PMID: 22454320

8

A new DPYD genotyping assay for improving the safety of 5-fluorouracil therapy.

Sistonen J, Smith C, Fu YK, Largiadèr CR. Sistonen J, et al. Among authors: largiader cr. Clin Chim Acta. 2012 Dec 24;414:109-11. doi: 10.1016/j.cca.2012.08.015. Epub 2012 Aug 23. Clin Chim Acta. 2012. PMID: 22935545

9

Gender-specific elimination of continuous-infusional 5-fluorouracil in patients with gastrointestinal malignancies: results from a prospective population pharmacokinetic study.

Mueller F, Büchel B, Köberle D, Schürch S, Pfister B, Krähenbühl S, Froehlich TK, Largiader CR, Joerger M. Mueller F, et al. Among authors: largiader cr. Cancer Chemother Pharmacol. 2013 Feb;71(2):361-70. doi: 10.1007/s00280-012-2018-4. Epub 2012 Nov 9. Cancer Chemother Pharmacol. 2013. PMID: 23139054 Free article.

10

Clinical importance of risk variants in the dihydropyrimidine dehydrogenase gene for the prediction of early-onset fluoropyrimidine toxicity.

Froehlich TK, Amstutz U, Aebi S, Joerger M, Largiadèr CR. Froehlich TK, et al. Among authors: largiader cr. Int J Cancer. 2015 Feb 1;136(3):730-9. doi: 10.1002/ijc.29025. Epub 2014 Jun 27. Int J Cancer. 2015. PMID: 24923815

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