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Protein Kinase A (PKA) Type I Interacts with P-Rex1, a Rac Guanine Nucleotide Exchange Factor: EFFECT ON PKA LOCALIZATION AND P-Rex1 SIGNALING.
Chávez-Vargas L, Adame-García SR, Cervantes-Villagrana RD, Castillo-Kauil A, Bruystens JG, Fukuhara S, Taylor SS, Mochizuki N, Reyes-Cruz G, Vázquez-Prado J. Chávez-Vargas L, et al. J Biol Chem. 2016 Mar 18;291(12):6182-99. doi: 10.1074/jbc.M115.712216. Epub 2016 Jan 21. J Biol Chem. 2016. PMID: 26797121 Free PMC article.
Gβγ signaling to the chemotactic effector P-REX1 and mammalian cell migration is directly regulated by Gαq and Gα13 proteins.
Cervantes-Villagrana RD, Adame-García SR, García-Jiménez I, Color-Aparicio VM, Beltrán-Navarro YM, König GM, Kostenis E, Reyes-Cruz G, Gutkind JS, Vázquez-Prado J. Cervantes-Villagrana RD, et al. J Biol Chem. 2019 Jan 11;294(2):531-546. doi: 10.1074/jbc.RA118.006254. Epub 2018 Nov 16. J Biol Chem. 2019. PMID: 30446620 Free PMC article.
Direct targeting of Gαq and Gα11 oncoproteins in cancer cells.
Annala S, Feng X, Shridhar N, Eryilmaz F, Patt J, Yang J, Pfeil EM, Cervantes-Villagrana RD, Inoue A, Häberlein F, Slodczyk T, Reher R, Kehraus S, Monteleone S, Schrage R, Heycke N, Rick U, Engel S, Pfeifer A, Kolb P, König G, Bünemann M, Tüting T, Vázquez-Prado J, Gutkind JS, Gaffal E, Kostenis E. Annala S, et al. Sci Signal. 2019 Mar 19;12(573):eaau5948. doi: 10.1126/scisignal.aau5948. Sci Signal. 2019. PMID: 30890659
Gαs directly drives PDZ-RhoGEF signaling to Cdc42.
Castillo-Kauil A, García-Jiménez I, Cervantes-Villagrana RD, Adame-García SR, Beltrán-Navarro YM, Gutkind JS, Reyes-Cruz G, Vázquez-Prado J. Castillo-Kauil A, et al. Among authors: cervantes villagrana rd. J Biol Chem. 2020 Dec 11;295(50):16920-16928. doi: 10.1074/jbc.AC120.015204. Epub 2020 Oct 6. J Biol Chem. 2020. PMID: 33023908 Free PMC article.
Gβγ recruits and activates P-Rex1 via two independent binding interfaces.
Cervantes-Villagrana RD, Beltrán-Navarro YM, García-Jiménez I, Adame-García SR, Olguín-Olguín A, Reyes-Cruz G, Vázquez-Prado J. Cervantes-Villagrana RD, et al. Biochem Biophys Res Commun. 2021 Feb 5;539:20-27. doi: 10.1016/j.bbrc.2020.12.089. Epub 2021 Jan 4. Biochem Biophys Res Commun. 2021. PMID: 33412417
[No title available]
[No authors listed] [No authors listed] PMID: 33453947
23 results