Vanover KE - Search Results

1

Discovery of Potent and Selective Inhibitors of Phosphodiesterase 1 for the Treatment of Cognitive Impairment Associated with Neurodegenerative and Neuropsychiatric Diseases.

Li P, Zheng H, Zhao J, Zhang L, Yao W, Zhu H, Beard JD, Ida K, Lane W, Snell G, Sogabe S, Heyser CJ, Snyder GL, Hendrick JP, Vanover KE, Davis RE, Wennogle LP. Li P, et al. Among authors: vanover ke. J Med Chem. 2016 Feb 11;59(3):1149-64. doi: 10.1021/acs.jmedchem.5b01751. Epub 2016 Feb 2. J Med Chem. 2016. PMID: 26789933

2

Psychosis of Parkinson's disease: serotonin 2A receptor inverse agonists as potential therapeutics.

Weiner DM, Vanover KE, Brann MR, Meltzer HY, Davis RE. Weiner DM, et al. Among authors: vanover ke. Curr Opin Investig Drugs. 2003 Jul;4(7):815-9. Curr Opin Investig Drugs. 2003. PMID: 14619402 Review.

3

Pharmacokinetics, tolerability, and safety of ACP-103 following single or multiple oral dose administration in healthy volunteers.

Vanover KE, Robbins-Weilert D, Wilbraham DG, Mant TG, van Kammen DP, Davis RE, Weiner DM. Vanover KE, et al. J Clin Pharmacol. 2007 Jun;47(6):704-14. doi: 10.1177/0091270007299431. Epub 2007 May 1. J Clin Pharmacol. 2007. PMID: 17473118 Clinical Trial.

4

ACP-103, a 5-hydroxytryptamine 2A receptor inverse agonist, improves the antipsychotic efficacy and side-effect profile of haloperidol and risperidone in experimental models.

Gardell LR, Vanover KE, Pounds L, Johnson RW, Barido R, Anderson GT, Veinbergs I, Dyssegaard A, Brunmark P, Tabatabaei A, Davis RE, Brann MR, Hacksell U, Bonhaus DW. Gardell LR, et al. Among authors: vanover ke. J Pharmacol Exp Ther. 2007 Aug;322(2):862-70. doi: 10.1124/jpet.107.121715. Epub 2007 May 22. J Pharmacol Exp Ther. 2007. PMID: 17519387

5

Antipsychotic-like behavioral effects and cognitive enhancement by a potent and selective muscarinic M-sub-1 receptor agonist, AC-260584.

Vanover KE, Veinbergs I, Davis RE. Vanover KE, et al. Behav Neurosci. 2008 Jun;122(3):570-5. doi: 10.1037/0735-7044.122.3.570. Behav Neurosci. 2008. PMID: 18513127

6

A 5-HT2A receptor inverse agonist, ACP-103, reduces tremor in a rat model and levodopa-induced dyskinesias in a monkey model.

Vanover KE, Betz AJ, Weber SM, Bibbiani F, Kielaite A, Weiner DM, Davis RE, Chase TN, Salamone JD. Vanover KE, et al. Pharmacol Biochem Behav. 2008 Oct;90(4):540-4. doi: 10.1016/j.pbb.2008.04.010. Pharmacol Biochem Behav. 2008. PMID: 18534670 Free PMC article.

7

Pimavanserin tartrate, a 5-HT(2A) receptor inverse agonist, increases slow wave sleep as measured by polysomnography in healthy adult volunteers.

Ancoli-Israel S, Vanover KE, Weiner DM, Davis RE, van Kammen DP. Ancoli-Israel S, et al. Among authors: vanover ke. Sleep Med. 2011 Feb;12(2):134-41. doi: 10.1016/j.sleep.2010.10.004. Epub 2011 Jan 21. Sleep Med. 2011. PMID: 21256805 Free PMC article. Clinical Trial.

8

Role of 5-HT2A receptor antagonists in the treatment of insomnia.

Vanover KE, Davis RE. Vanover KE, et al. Nat Sci Sleep. 2010 Jul 28;2:139-50. doi: 10.2147/nss.s6849. Print 2010. Nat Sci Sleep. 2010. PMID: 23616706 Free PMC article.

9

Intracellular signaling and approaches to the treatment of schizophrenia and associated cognitive impairment.

Snyder GL, Vanover KE. Snyder GL, et al. Among authors: vanover ke. Curr Pharm Des. 2014;20(31):5093-103. doi: 10.2174/1381612819666131216115417. Curr Pharm Des. 2014. PMID: 24345266 Review.

10

Discovery of a tetracyclic quinoxaline derivative as a potent and orally active multifunctional drug candidate for the treatment of neuropsychiatric and neurological disorders.

Li P, Zhang Q, Robichaud AJ, Lee T, Tomesch J, Yao W, Beard JD, Snyder GL, Zhu H, Peng Y, Hendrick JP, Vanover KE, Davis RE, Mates S, Wennogle LP. Li P, et al. Among authors: vanover ke. J Med Chem. 2014 Mar 27;57(6):2670-82. doi: 10.1021/jm401958n. Epub 2014 Mar 5. J Med Chem. 2014. PMID: 24559051

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