Stijnen P - Search Results

1

Endoplasmic reticulum-associated degradation of the mouse PC1/3-N222D hypomorph and human PCSK1 mutations contributes to obesity.

Stijnen P, Brouwers B, Dirkx E, Ramos-Molina B, Van Lommel L, Schuit F, Thorrez L, Declercq J, Creemers JW. Stijnen P, et al. Int J Obes (Lond). 2016 Jun;40(6):973-81. doi: 10.1038/ijo.2016.3. Epub 2016 Jan 20. Int J Obes (Lond). 2016. PMID: 26786350

2

A nonsense loss-of-function mutation in PCSK1 contributes to dominantly inherited human obesity.

Philippe J, Stijnen P, Meyre D, De Graeve F, Thuillier D, Delplanque J, Gyapay G, Sand O, Creemers JW, Froguel P, Bonnefond A. Philippe J, et al. Among authors: stijnen p. Int J Obes (Lond). 2015 Feb;39(2):295-302. doi: 10.1038/ijo.2014.96. Epub 2014 Jun 3. Int J Obes (Lond). 2015. PMID: 24890885

3

PCSK1 Mutations and Human Endocrinopathies: From Obesity to Gastrointestinal Disorders.

Stijnen P, Ramos-Molina B, O'Rahilly S, Creemers JW. Stijnen P, et al. Endocr Rev. 2016 Aug;37(4):347-71. doi: 10.1210/er.2015-1117. Epub 2016 May 17. Endocr Rev. 2016. PMID: 27187081 Review.

4

Genetic and functional characterization of PCSK1.

Choquet H, Stijnen P, Creemers JW. Choquet H, et al. Among authors: stijnen p. Methods Mol Biol. 2011;768:247-53. doi: 10.1007/978-1-61779-204-5_13. Methods Mol Biol. 2011. PMID: 21805247

5

Heterozygous mutations causing partial prohormone convertase 1 deficiency contribute to human obesity.

Creemers JW, Choquet H, Stijnen P, Vatin V, Pigeyre M, Beckers S, Meulemans S, Than ME, Yengo L, Tauber M, Balkau B, Elliott P, Jarvelin MR, Van Hul W, Van Gaal L, Horber F, Pattou F, Froguel P, Meyre D. Creemers JW, et al. Among authors: stijnen p. Diabetes. 2012 Feb;61(2):383-90. doi: 10.2337/db11-0305. Epub 2011 Dec 30. Diabetes. 2012. PMID: 22210313 Free PMC article.

6

Liver-Specific Inactivation of the Proprotein Convertase FURIN Leads to Increased Hepatocellular Carcinoma Growth.

Declercq J, Brouwers B, Pruniau VP, Stijnen P, Tuand K, Meulemans S, Prat A, Seidah NG, Khatib AM, Creemers JW. Declercq J, et al. Among authors: stijnen p. Biomed Res Int. 2015;2015:148651. doi: 10.1155/2015/148651. Epub 2015 Jun 8. Biomed Res Int. 2015. PMID: 26167473 Free PMC article.

7

The authors reply.

Stijnen P, Tuand K, Varga TV, Franks PW, Aertgeerts B, Creemers JW. Stijnen P, et al. Am J Epidemiol. 2015 May 1;181(9):733-4. doi: 10.1093/aje/kwv061. Epub 2015 Apr 9. Am J Epidemiol. 2015. PMID: 25861817 No abstract available.

8

Metabolic and Behavioural Phenotypes in Nestin-Cre Mice Are Caused by Hypothalamic Expression of Human Growth Hormone.

Declercq J, Brouwers B, Pruniau VP, Stijnen P, de Faudeur G, Tuand K, Meulemans S, Serneels L, Schraenen A, Schuit F, Creemers JW. Declercq J, et al. Among authors: stijnen p. PLoS One. 2015 Aug 14;10(8):e0135502. doi: 10.1371/journal.pone.0135502. eCollection 2015. PLoS One. 2015. PMID: 26275221 Free PMC article.

9

The association of common variants in PCSK1 with obesity: a HuGE review and meta-analysis.

Stijnen P, Tuand K, Varga TV, Franks PW, Aertgeerts B, Creemers JW. Stijnen P, et al. Am J Epidemiol. 2014 Dec 1;180(11):1051-65. doi: 10.1093/aje/kwu237. Epub 2014 Oct 29. Am J Epidemiol. 2014. PMID: 25355447 Review.

10

The dwarf phenotype in GH240B mice, haploinsufficient for the autism candidate gene Neurobeachin, is caused by ectopic expression of recombinant human growth hormone.

Nuytens K, Tuand K, Fu Q, Stijnen P, Pruniau V, Meulemans S, Vankelecom H, Creemers JW. Nuytens K, et al. Among authors: stijnen p. PLoS One. 2014 Oct 15;9(10):e109598. doi: 10.1371/journal.pone.0109598. eCollection 2014. PLoS One. 2014. PMID: 25333629 Free PMC article.

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