Liu-Chen LY - Search Results

1

Two short-acting kappa opioid receptor antagonists (zyklophin and LY2444296) exhibited different behavioral effects from the long-acting antagonist norbinaltorphimine in mouse anxiety tests.

Huang P, Yakovleva T, Aldrich JV, Tunis J, Parry C, Liu-Chen LY. Huang P, et al. Neurosci Lett. 2016 Feb 26;615:15-20. doi: 10.1016/j.neulet.2016.01.017. Epub 2016 Jan 15. Neurosci Lett. 2016. PMID: 26780565 Free PMC article.

2

The local environment at the cytoplasmic end of TM6 of the mu opioid receptor differs from those of rhodopsin and monoamine receptors: introduction of an ionic lock between the cytoplasmic ends of helices 3 and 6 by a L6.30(275)E mutation inactivates the mu opioid receptor and reduces the constitutive activity of its T6.34(279)K mutant.

Huang P, Visiers I, Weinstein H, Liu-Chen LY. Huang P, et al. Biochemistry. 2002 Oct 8;41(40):11972-80. doi: 10.1021/bi026067b. Biochemistry. 2002. PMID: 12356297

3

Differential effects of agonists on adenylyl cyclase superactivation mediated by the kappa opioid receptors: adenylyl cyclase superactivation is independent of agonist-induced phosphorylation, desensitization, internalization, and down-regulation.

Wang Y, Li JG, Huang P, Xu W, Liu-Chen LY. Wang Y, et al. J Pharmacol Exp Ther. 2003 Dec;307(3):1127-34. doi: 10.1124/jpet.103.055814. Epub 2003 Oct 13. J Pharmacol Exp Ther. 2003. PMID: 14557376

4

kappa Opioid receptor interacts with Na(+)/H(+)-exchanger regulatory factor-1/Ezrin-radixin-moesin-binding phosphoprotein-50 (NHERF-1/EBP50) to stimulate Na(+)/H(+) exchange independent of G(i)/G(o) proteins.

Huang P, Steplock D, Weinman EJ, Hall RA, Ding Z, Li J, Wang Y, Liu-Chen LY. Huang P, et al. J Biol Chem. 2004 Jun 11;279(24):25002-9. doi: 10.1074/jbc.M313366200. Epub 2004 Apr 7. J Biol Chem. 2004. PMID: 15070904 Free article.

5

Comparison of pharmacological activities of three distinct kappa ligands (Salvinorin A, TRK-820 and 3FLB) on kappa opioid receptors in vitro and their antipruritic and antinociceptive activities in vivo.

Wang Y, Tang K, Inan S, Siebert D, Holzgrabe U, Lee DY, Huang P, Li JG, Cowan A, Liu-Chen LY. Wang Y, et al. J Pharmacol Exp Ther. 2005 Jan;312(1):220-30. doi: 10.1124/jpet.104.073668. Epub 2004 Sep 21. J Pharmacol Exp Ther. 2005. PMID: 15383632

6

GEC1 interacts with the kappa opioid receptor and enhances expression of the receptor.

Chen C, Li JG, Chen Y, Huang P, Wang Y, Liu-Chen LY. Chen C, et al. J Biol Chem. 2006 Mar 24;281(12):7983-93. doi: 10.1074/jbc.M509805200. Epub 2006 Jan 23. J Biol Chem. 2006. PMID: 16431922 Free article.

7

Localization of the kappa opioid receptor in lipid rafts.

Xu W, Yoon SI, Huang P, Wang Y, Chen C, Chong PL, Liu-Chen LY. Xu W, et al. J Pharmacol Exp Ther. 2006 Jun;317(3):1295-306. doi: 10.1124/jpet.105.099507. Epub 2006 Feb 27. J Pharmacol Exp Ther. 2006. PMID: 16505160

8

Cholesterol reduction by methyl-beta-cyclodextrin attenuates the delta opioid receptor-mediated signaling in neuronal cells but enhances it in non-neuronal cells.

Huang P, Xu W, Yoon SI, Chen C, Chong PL, Liu-Chen LY. Huang P, et al. Biochem Pharmacol. 2007 Feb 15;73(4):534-49. doi: 10.1016/j.bcp.2006.10.032. Epub 2006 Nov 3. Biochem Pharmacol. 2007. PMID: 17141202 Free PMC article.

9

Brain region-specific N-glycosylation and lipid rafts association of the rat mu opioid receptor.

Huang P, Chen C, Xu W, Yoon SI, Unterwald EM, Pintar JE, Wang Y, Chong PL, Liu-Chen LY. Huang P, et al. Biochem Biophys Res Commun. 2008 Jan 4;365(1):82-8. doi: 10.1016/j.bbrc.2007.10.128. Epub 2007 Oct 31. Biochem Biophys Res Commun. 2008. PMID: 17980152 Free PMC article.

10

Agonist treatment did not affect association of mu opioid receptors with lipid rafts and cholesterol reduction had opposite effects on the receptor-mediated signaling in rat brain and CHO cells.

Huang P, Xu W, Yoon SI, Chen C, Chong PL, Unterwald EM, Liu-Chen LY. Huang P, et al. Brain Res. 2007 Dec 12;1184:46-56. doi: 10.1016/j.brainres.2007.09.096. Epub 2007 Oct 12. Brain Res. 2007. PMID: 17980352 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

181 results

Search Page

Filters