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Entecavir Interacts with Influx Transporters hOAT1, hCNT2, hCNT3, but Not with hOCT2: The Potential for Renal Transporter-Mediated Cytotoxicity and Drug-Drug Interactions.
Mandíková J, Volková M, Pávek P, Navrátilová L, Hyršová L, Janeba Z, Pavlík J, Bárta P, Trejtnar F. Mandíková J, et al. Among authors: janeba z. Front Pharmacol. 2016 Jan 5;6:304. doi: 10.3389/fphar.2015.00304. eCollection 2015. Front Pharmacol. 2016. PMID: 26779022 Free PMC article.
Bisamidate Prodrugs of 2-Substituted 9-[2-(Phosphonomethoxy)ethyl]adenine (PMEA, adefovir) as Selective Inhibitors of Adenylate Cyclase Toxin from Bordetella pertussis.
Česnek M, Jansa P, Šmídková M, Mertlíková-Kaiserová H, Dračínský M, Brust TF, Pávek P, Trejtnar F, Watts VJ, Janeba Z. Česnek M, et al. Among authors: janeba z. ChemMedChem. 2015 Aug;10(8):1351-64. doi: 10.1002/cmdc.201500183. Epub 2015 Jul 1. ChemMedChem. 2015. PMID: 26136378
Antiviral activities of 2,6-diaminopurine-based acyclic nucleoside phosphonates against herpesviruses: In vitro study results with pseudorabies virus (PrV, SuHV-1).
Zouharova D, Lipenska I, Fojtikova M, Kulich P, Neca J, Slany M, Kovarcik K, Turanek-Knotigova P, Hubatka F, Celechovska H, Masek J, Koudelka S, Prochazka L, Eyer L, Plockova J, Bartheldyova E, Miller AD, Ruzek D, Raska M, Janeba Z, Turanek J. Zouharova D, et al. Among authors: janeba z. Vet Microbiol. 2016 Feb 29;184:84-93. doi: 10.1016/j.vetmic.2016.01.010. Epub 2016 Jan 18. Vet Microbiol. 2016. PMID: 26854349
Acyclic nucleoside phosphonates with 2-aminothiazole base as inhibitors of bacterial and mammalian adenylate cyclases.
Břehová P, Chaloupecká E, Česnek M, Skácel J, Dračínský M, Tloušťová E, Mertlíková-Kaiserová H, Soto-Velasquez MP, Watts VJ, Janeba Z. Břehová P, et al. Among authors: janeba z. Eur J Med Chem. 2021 Oct 15;222:113581. doi: 10.1016/j.ejmech.2021.113581. Epub 2021 May 28. Eur J Med Chem. 2021. PMID: 34102377 Free PMC article.
Design, Synthesis, Biological Evaluation, and Crystallographic Study of Novel Purine Nucleoside Phosphorylase Inhibitors.
Skácel J, Djukic S, Baszczyňski O, Kalčic F, Bílek T, Chalupský K, Kozák J, Dvořáková A, Tloušt'ová E, Král'ová Z, Šmídková M, Voldřich J, Rumlová M, Pachl P, Brynda J, Vučková T, Fábry M, Snášel J, Pichová I, Řezáčová P, Mertlíková-Kaiserová H, Janeba Z. Skácel J, et al. Among authors: janeba z. J Med Chem. 2023 May 25;66(10):6652-6681. doi: 10.1021/acs.jmedchem.2c02097. Epub 2023 May 3. J Med Chem. 2023. PMID: 37134237 Free PMC article.
Nucleobase Modified Adefovir (PMEA) Analogues as Potent and Selective Inhibitors of Adenylate Cyclases from Bordetella pertussis and Bacillus anthracis.
Česnek M, Skácel J, Jansa P, Dračínský M, Šmídková M, Mertlíková-Kaiserová H, Soto-Velasquez MP, Watts VJ, Janeba Z. Česnek M, et al. Among authors: janeba z. ChemMedChem. 2018 Sep 6;13(17):1779-1796. doi: 10.1002/cmdc.201800332. Epub 2018 Jul 31. ChemMedChem. 2018. PMID: 29968968 Free PMC article.
81 results