Iravani M - Search Results

1

Tumour cell-derived Wnt7a recruits and activates fibroblasts to promote tumour aggressiveness.

Avgustinova A, Iravani M, Robertson D, Fearns A, Gao Q, Klingbeil P, Hanby AM, Speirs V, Sahai E, Calvo F, Isacke CM. Avgustinova A, et al. Among authors: iravani m. Nat Commun. 2016 Jan 18;7:10305. doi: 10.1038/ncomms10305. Nat Commun. 2016. PMID: 26777421 Free PMC article.

2

Genome-wide transcriptomic profiling of microdissected human breast tissue reveals differential expression of KIT (c-Kit, CD117) and oestrogen receptor-alpha (ERalpha) in response to therapeutic radiation.

Westbury CB, Reis-Filho JS, Dexter T, Mahler-Araujo B, Fenwick K, Iravani M, Grigoriadis A, Parry S, Robertson D, Mackay A, Ashworth A, Yarnold JR, Isacke CM. Westbury CB, et al. Among authors: iravani m. J Pathol. 2009 Sep;219(1):131-40. doi: 10.1002/path.2581. J Pathol. 2009. PMID: 19562735

3

A role for fibrillar collagen deposition and the collagen internalization receptor endo180 in glioma invasion.

Huijbers IJ, Iravani M, Popov S, Robertson D, Al-Sarraj S, Jones C, Isacke CM. Huijbers IJ, et al. Among authors: iravani m. PLoS One. 2010 Mar 22;5(3):e9808. doi: 10.1371/journal.pone.0009808. PLoS One. 2010. PMID: 20339555 Free PMC article.

4

An in vivo functional screen identifies ST6GalNAc2 sialyltransferase as a breast cancer metastasis suppressor.

Murugaesu N, Iravani M, van Weverwijk A, Ivetic A, Johnson DA, Antonopoulos A, Fearns A, Jamal-Hanjani M, Sims D, Fenwick K, Mitsopoulos C, Gao Q, Orr N, Zvelebil M, Haslam SM, Dell A, Yarwood H, Lord CJ, Ashworth A, Isacke CM. Murugaesu N, et al. Among authors: iravani m. Cancer Discov. 2014 Mar;4(3):304-17. doi: 10.1158/2159-8290.CD-13-0287. Epub 2014 Feb 11. Cancer Discov. 2014. PMID: 24520024

5

An In Vivo Functional Screen Identifies JNK Signaling As a Modulator of Chemotherapeutic Response in Breast Cancer.

Ashenden M, van Weverwijk A, Murugaesu N, Fearns A, Campbell J, Gao Q, Iravani M, Isacke CM. Ashenden M, et al. Among authors: iravani m. Mol Cancer Ther. 2017 Sep;16(9):1967-1978. doi: 10.1158/1535-7163.MCT-16-0731. Epub 2017 Jun 13. Mol Cancer Ther. 2017. PMID: 28611109

6

Using an in-vivo syngeneic spontaneous metastasis model identifies ID2 as a promoter of breast cancer colonisation in the brain.

Kijewska M, Viski C, Turrell F, Fitzpatrick A, van Weverwijk A, Gao Q, Iravani M, Isacke CM. Kijewska M, et al. Among authors: iravani m. Breast Cancer Res. 2019 Jan 14;21(1):4. doi: 10.1186/s13058-018-1093-9. Breast Cancer Res. 2019. PMID: 30642388 Free PMC article.

7

Metabolic adaptability in metastatic breast cancer by AKR1B10-dependent balancing of glycolysis and fatty acid oxidation.

van Weverwijk A, Koundouros N, Iravani M, Ashenden M, Gao Q, Poulogiannis G, Jungwirth U, Isacke CM. van Weverwijk A, et al. Among authors: iravani m. Nat Commun. 2019 Jun 20;10(1):2698. doi: 10.1038/s41467-019-10592-4. Nat Commun. 2019. PMID: 31221959 Free PMC article.

8

Impairment of a distinct cancer-associated fibroblast population limits tumour growth and metastasis.

Jungwirth U, van Weverwijk A, Evans RJ, Jenkins L, Vicente D, Alexander J, Gao Q, Haider S, Iravani M, Isacke CM. Jungwirth U, et al. Among authors: iravani m. Nat Commun. 2021 Jun 10;12(1):3516. doi: 10.1038/s41467-021-23583-1. Nat Commun. 2021. PMID: 34112782 Free PMC article.

9

Assessing CSF ctDNA to Improve Diagnostic Accuracy and Therapeutic Monitoring in Breast Cancer Leptomeningeal Metastasis.

Fitzpatrick A, Iravani M, Mills A, Childs L, Alaguthurai T, Clifford A, Garcia-Murillas I, Van Laere S, Dirix L, Harries M, Okines A, Turner NC, Haider S, Tutt ANJ, Isacke CM. Fitzpatrick A, et al. Among authors: iravani m. Clin Cancer Res. 2022 Mar 15;28(6):1180-1191. doi: 10.1158/1078-0432.CCR-21-3017. Clin Cancer Res. 2022. PMID: 34921020 Free PMC article.

10

Cancer-Associated Fibroblasts Suppress CD8+ T-cell Infiltration and Confer Resistance to Immune-Checkpoint Blockade.

Jenkins L, Jungwirth U, Avgustinova A, Iravani M, Mills A, Haider S, Harper J, Isacke CM. Jenkins L, et al. Among authors: iravani m. Cancer Res. 2022 Aug 16;82(16):2904-2917. doi: 10.1158/0008-5472.CAN-21-4141. Cancer Res. 2022. PMID: 35749591 Free PMC article.

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