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Agonists of proteinase-activated receptor-2 stimulate upregulation of intercellular cell adhesion molecule-1 in primary human keratinocytes via activation of NF-kappa B.
Buddenkotte J, Stroh C, Engels IH, Moormann C, Shpacovitch VM, Seeliger S, Vergnolle N, Vestweber D, Luger TA, Schulze-Osthoff K, Steinhoff M. Buddenkotte J, et al. J Invest Dermatol. 2005 Jan;124(1):38-45. doi: 10.1111/j.0022-202X.2004.23539.x. J Invest Dermatol. 2005. PMID: 15654951 Free article.
IκBζ is a key driver in the development of psoriasis.
Johansen C, Mose M, Ommen P, Bertelsen T, Vinter H, Hailfinger S, Lorscheid S, Schulze-Osthoff K, Iversen L. Johansen C, et al. Proc Natl Acad Sci U S A. 2015 Oct 27;112(43):E5825-33. doi: 10.1073/pnas.1509971112. Epub 2015 Oct 12. Proc Natl Acad Sci U S A. 2015. PMID: 26460049 Free PMC article.
340 results