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Page 1
The low EOMES/TBX21 molecular phenotype in multiple sclerosis reflects CD56+ cell dysregulation and is affected by immunomodulatory therapies.
McKay FC, Gatt PN, Fewings N, Parnell GP, Schibeci SD, Basuki MA, Powell JE, Goldinger A, Fabis-Pedrini MJ, Kermode AG, Burke T, Vucic S, Stewart GJ, Booth DR. McKay FC, et al. Among authors: gatt pn. Clin Immunol. 2016 Feb;163:96-107. doi: 10.1016/j.clim.2015.12.015. Epub 2016 Jan 4. Clin Immunol. 2016. PMID: 26762769
Ribosomal protein S6 mRNA is a biomarker upregulated in multiple sclerosis, downregulated by interferon treatment, and affected by season.
Parnell GP, Gatt PN, McKay FC, Schibeci S, Krupa M, Powell JE, Visscher PM, Montgomery GW, Lechner-Scott J, Broadley S, Liddle C, Slee M, Vucic S, Stewart GJ, Booth DR. Parnell GP, et al. Among authors: gatt pn. Mult Scler. 2014 May;20(6):675-85. doi: 10.1177/1352458513507819. Epub 2013 Oct 14. Mult Scler. 2014. PMID: 24126065
The CYP27B1 variant associated with an increased risk of autoimmune disease is underexpressed in tolerizing dendritic cells.
Shahijanian F, Parnell GP, McKay FC, Gatt PN, Shojoei M, O'Connor KS, Schibeci SD, Brilot F, Liddle C, Batten M; ANZgene Multiple Sclerosis Genetics Consortium; Stewart GJ, Booth DR. Shahijanian F, et al. Among authors: gatt pn. Hum Mol Genet. 2014 Mar 15;23(6):1425-34. doi: 10.1093/hmg/ddt529. Epub 2013 Oct 24. Hum Mol Genet. 2014. PMID: 24158849
The autoimmune disease-associated transcription factors EOMES and TBX21 are dysregulated in multiple sclerosis and define a molecular subtype of disease.
Parnell GP, Gatt PN, Krupa M, Nickles D, McKay FC, Schibeci SD, Batten M, Baranzini S, Henderson A, Barnett M, Slee M, Vucic S, Stewart GJ, Booth DR. Parnell GP, et al. Among authors: gatt pn. Clin Immunol. 2014 Mar;151(1):16-24. doi: 10.1016/j.clim.2014.01.003. Epub 2014 Jan 15. Clin Immunol. 2014. PMID: 24495857 Free article.
Response to interferon-beta treatment in multiple sclerosis patients: a genome-wide association study.
Mahurkar S, Moldovan M, Suppiah V, Sorosina M, Clarelli F, Liberatore G, Malhotra S, Montalban X, Antigüedad A, Krupa M, Jokubaitis VG, McKay FC, Gatt PN, Fabis-Pedrini MJ, Martinelli V, Comi G, Lechner-Scott J, Kermode AG, Slee M, Taylor BV, Vandenbroeck K, Comabella M, Boneschi FM; Australian and New Zealand Multiple Sclerosis Genetics Consortium (ANZgene); King C. Mahurkar S, et al. Among authors: gatt pn. Pharmacogenomics J. 2017 Jul;17(4):312-318. doi: 10.1038/tpj.2016.20. Epub 2016 Mar 22. Pharmacogenomics J. 2017. PMID: 27001119
The autoimmune risk gene ZMIZ1 is a vitamin D responsive marker of a molecular phenotype of multiple sclerosis.
Fewings NL, Gatt PN, McKay FC, Parnell GP, Schibeci SD, Edwards J, Basuki MA, Goldinger A, Fabis-Pedrini MJ, Kermode AG, Manrique CP, McCauley JL, Nickles D, Baranzini SE, Burke T, Vucic S, Stewart GJ, Booth DR. Fewings NL, et al. Among authors: gatt pn. J Autoimmun. 2017 Mar;78:57-69. doi: 10.1016/j.jaut.2016.12.006. Epub 2017 Jan 4. J Autoimmun. 2017. PMID: 28063629
Data characterizing the ZMIZ1 molecular phenotype of multiple sclerosis.
Fewings N, Gatt PN, McKay FC, Parnell GP, Schibeci SD, Edwards J, Basuki MA, Goldinger A, Fabis-Pedrini MJ, Kermode AG, Manrique CP, McCauley JL, Nickles D, Baranzini SE, Burke T, Vucic S, Stewart GJ, Booth DR. Fewings N, et al. Among authors: gatt pn. Data Brief. 2017 Feb 21;11:364-370. doi: 10.1016/j.dib.2017.02.040. eCollection 2017 Apr. Data Brief. 2017. PMID: 28275670 Free PMC article.
Expression of CYP24A1 and other multiple sclerosis risk genes in peripheral blood indicates response to vitamin D in homeostatic and inflammatory conditions.
Law SPL, Gatt PN, Schibeci SD, McKay FC, Vucic S, Hart P, Byrne SN, Brown D, Stewart GJ, Liddle C, Parnell GP, Booth DR. Law SPL, et al. Among authors: gatt pn. Genes Immun. 2021 Aug;22(4):227-233. doi: 10.1038/s41435-021-00144-6. Epub 2021 Jun 23. Genes Immun. 2021. PMID: 34163021 Free PMC article.
Antibodies to myelin oligodendrocyte glycoprotein in bilateral and recurrent optic neuritis.
Ramanathan S, Reddel SW, Henderson A, Parratt JD, Barnett M, Gatt PN, Merheb V, Kumaran RY, Pathmanandavel K, Sinmaz N, Ghadiri M, Yiannikas C, Vucic S, Stewart G, Bleasel AF, Booth D, Fung VS, Dale RC, Brilot F. Ramanathan S, et al. Among authors: gatt pn. Neurol Neuroimmunol Neuroinflamm. 2014 Oct 29;1(4):e40. doi: 10.1212/NXI.0000000000000040. eCollection 2014 Dec. Neurol Neuroimmunol Neuroinflamm. 2014. PMID: 25364774 Free PMC article.
13 results