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Mitochondrial iron chelation ameliorates cigarette smoke-induced bronchitis and emphysema in mice.
Cloonan SM, Glass K, Laucho-Contreras ME, Bhashyam AR, Cervo M, Pabón MA, Konrad C, Polverino F, Siempos II, Perez E, Mizumura K, Ghosh MC, Parameswaran H, Williams NC, Rooney KT, Chen ZH, Goldklang MP, Yuan GC, Moore SC, Demeo DL, Rouault TA, D'Armiento JM, Schon EA, Manfredi G, Quackenbush J, Mahmood A, Silverman EK, Owen CA, Choi AM. Cloonan SM, et al. Among authors: choi am. Nat Med. 2016 Feb;22(2):163-74. doi: 10.1038/nm.4021. Epub 2016 Jan 11. Nat Med. 2016. PMID: 26752519 Free PMC article.
Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease.
Chen ZH, Kim HP, Sciurba FC, Lee SJ, Feghali-Bostwick C, Stolz DB, Dhir R, Landreneau RJ, Schuchert MJ, Yousem SA, Nakahira K, Pilewski JM, Lee JS, Zhang Y, Ryter SW, Choi AM. Chen ZH, et al. Among authors: choi am. PLoS One. 2008 Oct 2;3(10):e3316. doi: 10.1371/journal.pone.0003316. PLoS One. 2008. PMID: 18830406 Free PMC article.
Integration of genomic and genetic approaches implicates IREB2 as a COPD susceptibility gene.
DeMeo DL, Mariani T, Bhattacharya S, Srisuma S, Lange C, Litonjua A, Bueno R, Pillai SG, Lomas DA, Sparrow D, Shapiro SD, Criner GJ, Kim HP, Chen Z, Choi AM, Reilly J, Silverman EK. DeMeo DL, et al. Among authors: choi am. Am J Hum Genet. 2009 Oct;85(4):493-502. doi: 10.1016/j.ajhg.2009.09.004. Am J Hum Genet. 2009. PMID: 19800047 Free PMC article.
Autophagic protein LC3B confers resistance against hypoxia-induced pulmonary hypertension.
Lee SJ, Smith A, Guo L, Alastalo TP, Li M, Sawada H, Liu X, Chen ZH, Ifedigbo E, Jin Y, Feghali-Bostwick C, Ryter SW, Kim HP, Rabinovitch M, Choi AM. Lee SJ, et al. Among authors: choi am. Am J Respir Crit Care Med. 2011 Mar 1;183(5):649-58. doi: 10.1164/rccm.201005-0746OC. Epub 2010 Oct 1. Am J Respir Crit Care Med. 2011. PMID: 20889906 Free PMC article.
424 results