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NDPK-D (NM23-H4)-mediated externalization of cardiolipin enables elimination of depolarized mitochondria by mitophagy.
Kagan VE, Jiang J, Huang Z, Tyurina YY, Desbourdes C, Cottet-Rousselle C, Dar HH, Verma M, Tyurin VA, Kapralov AA, Cheikhi A, Mao G, Stolz D, St Croix CM, Watkins S, Shen Z, Li Y, Greenberg ML, Tokarska-Schlattner M, Boissan M, Lacombe ML, Epand RM, Chu CT, Mallampalli RK, Bayır H, Schlattner U. Kagan VE, et al. Among authors: chu ct. Cell Death Differ. 2016 Jul;23(7):1140-51. doi: 10.1038/cdd.2015.160. Epub 2016 Jan 8. Cell Death Differ. 2016. PMID: 26742431 Free PMC article.
The "pro-apoptotic genies" get out of mitochondria: oxidative lipidomics and redox activity of cytochrome c/cardiolipin complexes.
Kagan VE, Tyurina YY, Bayir H, Chu CT, Kapralov AA, Vlasova II, Belikova NA, Tyurin VA, Amoscato A, Epperly M, Greenberger J, Dekosky S, Shvedova AA, Jiang J. Kagan VE, et al. Among authors: chu ct. Chem Biol Interact. 2006 Oct 27;163(1-2):15-28. doi: 10.1016/j.cbi.2006.04.019. Epub 2006 May 12. Chem Biol Interact. 2006. PMID: 16797512 Review.
Starving neurons show sex difference in autophagy.
Du L, Hickey RW, Bayir H, Watkins SC, Tyurin VA, Guo F, Kochanek PM, Jenkins LW, Ren J, Gibson G, Chu CT, Kagan VE, Clark RS. Du L, et al. Among authors: chu ct. J Biol Chem. 2009 Jan 23;284(4):2383-96. doi: 10.1074/jbc.M804396200. Epub 2008 Nov 25. J Biol Chem. 2009. PMID: 19036730 Free PMC article.
Peroxidase mechanism of lipid-dependent cross-linking of synuclein with cytochrome C: protection against apoptosis versus delayed oxidative stress in Parkinson disease.
Bayir H, Kapralov AA, Jiang J, Huang Z, Tyurina YY, Tyurin VA, Zhao Q, Belikova NA, Vlasova II, Maeda A, Zhu J, Na HM, Mastroberardino PG, Sparvero LJ, Amoscato AA, Chu CT, Greenamyre JT, Kagan VE. Bayir H, et al. Among authors: chu ct. J Biol Chem. 2009 Jun 5;284(23):15951-69. doi: 10.1074/jbc.M900418200. Epub 2009 Apr 7. J Biol Chem. 2009. PMID: 19351880 Free PMC article.
224 results