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Identification of a novel drug lead that inhibits HCV infection and cell-to-cell transmission by targeting the HCV E2 glycoprotein.
Al Olaby RR, Cocquerel L, Zemla A, Saas L, Dubuisson J, Vielmetter J, Marcotrigiano J, Khan AG, Vences Catalan F, Perryman AL, Freundlich JS, Forli S, Levy S, Balhorn R, Azzazy HM. Al Olaby RR, et al. Among authors: khan ag. PLoS One. 2014 Oct 30;9(10):e111333. doi: 10.1371/journal.pone.0111333. eCollection 2014. PLoS One. 2014. PMID: 25357246 Free PMC article.
The autoinhibitory CARD2-Hel2i Interface of RIG-I governs RNA selection.
Ramanathan A, Devarkar SC, Jiang F, Miller MT, Khan AG, Marcotrigiano J, Patel SS. Ramanathan A, et al. Among authors: khan ag. Nucleic Acids Res. 2016 Jan 29;44(2):896-909. doi: 10.1093/nar/gkv1299. Epub 2015 Nov 26. Nucleic Acids Res. 2016. PMID: 26612866 Free PMC article.
Regions of hepatitis C virus E2 required for membrane association.
Kumar A, Rohe TC, Elrod EJ, Khan AG, Dearborn AD, Kissinger R, Grakoui A, Marcotrigiano J. Kumar A, et al. Among authors: khan ag. Nat Commun. 2023 Jan 26;14(1):433. doi: 10.1038/s41467-023-36183-y. Nat Commun. 2023. PMID: 36702826 Free PMC article.
113 results