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Indigenous Arabs are descendants of the earliest split from ancient Eurasian populations.
Rodriguez-Flores JL, Fakhro K, Agosto-Perez F, Ramstetter MD, Arbiza L, Vincent TL, Robay A, Malek JA, Suhre K, Chouchane L, Badii R, Al-Nabet Al-Marri A, Abi Khalil C, Zirie M, Jayyousi A, Salit J, Keinan A, Clark AG, Crystal RG, Mezey JG. Rodriguez-Flores JL, et al. Among authors: chouchane l. Genome Res. 2016 Feb;26(2):151-62. doi: 10.1101/gr.191478.115. Epub 2016 Jan 4. Genome Res. 2016. PMID: 26728717 Free PMC article.
TNRC9 downregulates BRCA1 expression and promotes breast cancer aggressiveness.
Shan J, Dsouza SP, Bakhru S, Al-Azwani EK, Ascierto ML, Sastry KS, Bedri S, Kizhakayil D, Aigha II, Malek J, Al-Bozom I, Gehani S, Furtado S, Mathiowitz E, Wang E, Marincola FM, Chouchane L. Shan J, et al. Among authors: chouchane l. Cancer Res. 2013 May 1;73(9):2840-9. doi: 10.1158/0008-5472.CAN-12-4313. Epub 2013 Feb 27. Cancer Res. 2013. PMID: 23447579
Longitudinal study of recurrent metastatic melanoma cell lines underscores the individuality of cancer biology.
Pos Z, Spivey TL, Liu H, Sommariva M, Chen J, Wunderlich JR, Parisi G, Tomei S, Ayotte BD, Stroncek DF, Malek JA, Robbins PF, Rivoltini L, Maio M, Chouchane L, Wang E, Marincola FM. Pos Z, et al. Among authors: chouchane l. J Invest Dermatol. 2014 May;134(5):1389-1396. doi: 10.1038/jid.2013.495. Epub 2013 Nov 22. J Invest Dermatol. 2014. PMID: 24270663 Free PMC article.
Genetic predisposition to cancer across people of different ancestries in Qatar: a population-based, cohort study.
Saad M, Mokrab Y, Halabi N, Shan J, Razali R, Kunji K, Syed N, Temanni R, Subramanian M, Ceccarelli M; Qatar Genome Programme Research Consortium; Rafii Tabrizi A, Bedognetti D, Chouchane L. Saad M, et al. Among authors: chouchane l. Lancet Oncol. 2022 Mar;23(3):341-352. doi: 10.1016/S1470-2045(21)00752-X. Epub 2022 Feb 9. Lancet Oncol. 2022. PMID: 35150601
A population study of clinically actionable genetic variation affecting drug response from the Middle East.
Jithesh PV, Abuhaliqa M, Syed N, Ahmed I, El Anbari M, Bastaki K, Sherif S, Umlai UK, Jan Z, Gandhi G, Manickam C, Selvaraj S, George C, Bangarusamy D, Abdel-Latif R, Al-Shafai M, Tatari-Calderone Z, Estivill X, Pirmohamed M; Qatar Genome Program Research Consortium. Jithesh PV, et al. NPJ Genom Med. 2022 Feb 15;7(1):10. doi: 10.1038/s41525-022-00281-5. NPJ Genom Med. 2022. PMID: 35169154 Free PMC article.
171 results