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Identification of bacterial target proteins for the salicylidene acylhydrazide class of virulence-blocking compounds.
Wang D, Zetterström CE, Gabrielsen M, Beckham KS, Tree JJ, Macdonald SE, Byron O, Mitchell TJ, Gally DL, Herzyk P, Mahajan A, Uvell H, Burchmore R, Smith BO, Elofsson M, Roe AJ. Wang D, et al. Among authors: gabrielsen m. J Biol Chem. 2011 Aug 26;286(34):29922-31. doi: 10.1074/jbc.M111.233858. Epub 2011 Jul 1. J Biol Chem. 2011. PMID: 21724850 Free PMC article.
The structure of an orthorhombic crystal form of a 'forced reduced' thiol peroxidase reveals lattice formation aided by the presence of the affinity tag.
Beckham KS, Byron O, Roe AJ, Gabrielsen M. Beckham KS, et al. Among authors: gabrielsen m. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 May 1;68(Pt 5):522-6. doi: 10.1107/S1744309112011487. Epub 2012 Apr 20. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012. PMID: 22691780 Free PMC article.
Crystal structures of WrbA, a spurious target of the salicylidene acylhydrazide inhibitors of type III secretion in Gram-negative pathogens, and verification of improved specificity of next-generation compounds.
Zambelloni R, Beckham KSH, Wu HJ, Elofsson M, Marquez R, Gabrielsen M, Roe AJ. Zambelloni R, et al. Among authors: gabrielsen m. Microbiology (Reading). 2022 Jul;168(7). doi: 10.1099/mic.0.001211. Microbiology (Reading). 2022. PMID: 35829699 Free article.
151 results