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Page 1
The energy landscape of adenylate kinase during catalysis.
Kerns SJ, Agafonov RV, Cho YJ, Pontiggia F, Otten R, Pachov DV, Kutter S, Phung LA, Murphy PN, Thai V, Alber T, Hagan MF, Kern D. Kerns SJ, et al. Among authors: agafonov rv. Nat Struct Mol Biol. 2015 Feb;22(2):124-31. doi: 10.1038/nsmb.2941. Epub 2015 Jan 12. Nat Struct Mol Biol. 2015. PMID: 25580578 Free PMC article.
Dynamics of human protein kinase Aurora A linked to drug selectivity.
Pitsawong W, Buosi V, Otten R, Agafonov RV, Zorba A, Kern N, Kutter S, Kern G, Pádua RA, Meniche X, Kern D. Pitsawong W, et al. Among authors: agafonov rv. Elife. 2018 Jun 14;7:e36656. doi: 10.7554/eLife.36656. Elife. 2018. PMID: 29901437 Free PMC article.
Evolution and intelligent design in drug development.
Agafonov RV, Wilson C, Kern D. Agafonov RV, et al. Front Mol Biosci. 2015 May 21;2:27. doi: 10.3389/fmolb.2015.00027. eCollection 2015. Front Mol Biosci. 2015. PMID: 26052517 Free PMC article.
Drug targets evolve, and so should the methods.
Wilson C, Agafonov RV, Kern D. Wilson C, et al. Among authors: agafonov rv. Mol Cell Oncol. 2015 Nov 11;3(4):e1046580. doi: 10.1080/23723556.2015.1046580. eCollection 2016 Jul. Mol Cell Oncol. 2015. PMID: 27652309 Free PMC article.
Evolutionary drivers of thermoadaptation in enzyme catalysis.
Nguyen V, Wilson C, Hoemberger M, Stiller JB, Agafonov RV, Kutter S, English J, Theobald DL, Kern D. Nguyen V, et al. Among authors: agafonov rv. Science. 2017 Jan 20;355(6322):289-294. doi: 10.1126/science.aah3717. Epub 2016 Dec 22. Science. 2017. PMID: 28008087 Free PMC article.
A Method for Determining the Kinetics of Small-Molecule-Induced Ubiquitination.
Vieux EF, Agafonov RV, Emerson L, Isasa M, Deibler RW, Simard JR, Cocozziello D, Ladd B, Lee L, Li H, Archer S, Fitzgerald M, Michael R, Nasveschuk CG, Park ES, Kern G, Proia DA, Phillips AJ, Fisher SL. Vieux EF, et al. Among authors: agafonov rv. SLAS Discov. 2021 Apr;26(4):547-559. doi: 10.1177/24725552211000673. SLAS Discov. 2021. PMID: 33780296 Free article.
16 results