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AKAP150 participates in calcineurin/NFAT activation during the down-regulation of voltage-gated K(+) currents in ventricular myocytes following myocardial infarction.
Nieves-Cintrón M, Hirenallur-Shanthappa D, Nygren PJ, Hinke SA, Dell'Acqua ML, Langeberg LK, Navedo M, Santana LF, Scott JD. Nieves-Cintrón M, et al. Among authors: nygren pj. Cell Signal. 2016 Jul;28(7):733-40. doi: 10.1016/j.cellsig.2015.12.015. Epub 2015 Dec 24. Cell Signal. 2016. PMID: 26724383 Free PMC article.
AKAP150 contributes to enhanced vascular tone by facilitating large-conductance Ca2+-activated K+ channel remodeling in hyperglycemia and diabetes mellitus.
Nystoriak MA, Nieves-Cintrón M, Nygren PJ, Hinke SA, Nichols CB, Chen CY, Puglisi JL, Izu LT, Bers DM, Dell'acqua ML, Scott JD, Santana LF, Navedo MF. Nystoriak MA, et al. Among authors: nygren pj. Circ Res. 2014 Feb 14;114(4):607-15. doi: 10.1161/CIRCRESAHA.114.302168. Epub 2013 Dec 9. Circ Res. 2014. PMID: 24323672 Free PMC article.
Anchored phosphatases modulate glucose homeostasis.
Hinke SA, Navedo MF, Ulman A, Whiting JL, Nygren PJ, Tian G, Jimenez-Caliani AJ, Langeberg LK, Cirulli V, Tengholm A, Dell'Acqua ML, Santana LF, Scott JD. Hinke SA, et al. Among authors: nygren pj. EMBO J. 2012 Oct 17;31(20):3991-4004. doi: 10.1038/emboj.2012.244. Epub 2012 Aug 31. EMBO J. 2012. PMID: 22940692 Free PMC article.
Single nucleotide polymorphisms alter kinase anchoring and the subcellular targeting of A-kinase anchoring proteins.
Smith FD, Omar MH, Nygren PJ, Soughayer J, Hoshi N, Lau HT, Snyder CG, Branon TC, Ghosh D, Langeberg LK, Ting AY, Santana LF, Ong SE, Navedo MF, Scott JD. Smith FD, et al. Among authors: nygren pj. Proc Natl Acad Sci U S A. 2018 Dec 4;115(49):E11465-E11474. doi: 10.1073/pnas.1816614115. Epub 2018 Nov 19. Proc Natl Acad Sci U S A. 2018. PMID: 30455320 Free PMC article.
Local protein kinase A action proceeds through intact holoenzymes.
Smith FD, Esseltine JL, Nygren PJ, Veesler D, Byrne DP, Vonderach M, Strashnov I, Eyers CE, Eyers PA, Langeberg LK, Scott JD. Smith FD, et al. Among authors: nygren pj. Science. 2017 Jun 23;356(6344):1288-1293. doi: 10.1126/science.aaj1669. Science. 2017. PMID: 28642438 Free PMC article.
267 results