You Q - Search Results

1

Affinity-Based Fluorescence Polarization Assay for High-Throughput Screening of Prolyl Hydroxylase 2 Inhibitors.

Lei Y, Hu T, Wu X, Wu Y, Bao Q, Zhang L, Xia H, Sun H, You Q, Zhang X. Lei Y, et al. Among authors: you q. ACS Med Chem Lett. 2015 Nov 9;6(12):1236-40. doi: 10.1021/acsmedchemlett.5b00394. eCollection 2015 Dec 10. ACS Med Chem Lett. 2015. PMID: 26713111 Free PMC article.

2

Predicting the potency of hERG K⁺ channel inhibition by combining 3D-QSAR pharmacophore and 2D-QSAR models.

Tan Y, Chen Y, You Q, Sun H, Li M. Tan Y, et al. Among authors: you q. J Mol Model. 2012 Mar;18(3):1023-36. doi: 10.1007/s00894-011-1136-y. Epub 2011 Jun 10. J Mol Model. 2012. PMID: 21660488

3

Combination of pharmacophore model development and binding mode analyses: identification of ligand features essential for IκB kinase-beta (IKKβ) inhibitors and virtual screening based on it.

Sun HP, Zhu J, Chen FH, Zhang SL, Zhang Y, You QD. Sun HP, et al. Eur J Med Chem. 2011 Sep;46(9):3942-52. doi: 10.1016/j.ejmech.2011.05.066. Epub 2011 Jun 25. Eur J Med Chem. 2011. PMID: 21708416

4

Synthesis and evaluation of novel aza-caged Garcinia xanthones.

Zhang X, Li X, Sun H, Jiang Z, Tao L, Gao Y, Guo Q, You Q. Zhang X, et al. Among authors: you q. Org Biomol Chem. 2012 Apr 28;10(16):3288-99. doi: 10.1039/c2ob07088j. Epub 2012 Mar 12. Org Biomol Chem. 2012. PMID: 22407464

5

Studies on gambogic acid (IV): Exploring structure-activity relationship with IκB kinase-beta (IKKβ).

Sun H, Chen F, Wang X, Liu Z, Yang Q, Zhang X, Zhu J, Qiang L, Guo Q, You Q. Sun H, et al. Among authors: you q. Eur J Med Chem. 2012 May;51:110-23. doi: 10.1016/j.ejmech.2012.02.029. Epub 2012 Mar 3. Eur J Med Chem. 2012. PMID: 22472167

6

Synthesis, SAR and biological evaluation of natural and non-natural hydroxylated and prenylated xanthones as antitumor agents.

Zhang X, Li X, Ye S, Zhang Y, Tao L, Gao Y, Gong D, Xi M, Meng H, Zhang M, Gao W, Xu X, Guo Q, You Q. Zhang X, et al. Among authors: you q. Med Chem. 2012 Nov;8(6):1012-25. doi: 10.2174/1573406411208061012. Med Chem. 2012. PMID: 22779801

7

Studies on chemical structure modification and structure-activity relationship of derivatives of gambogic acid at C(39).

Sun HP, Liu ZL, Xue X, Gao Y, Zhang L, Wang JX, Guo QL, You QD. Sun HP, et al. Chem Biodivers. 2012 Aug;9(8):1579-90. doi: 10.1002/cbdv.201100415. Chem Biodivers. 2012. PMID: 22899618

8

LYG-202 augments tumor necrosis factor-α-induced apoptosis via attenuating casein kinase 2-dependent nuclear factor-κB pathway in HepG2 cells.

Chen FH, Lu N, Zhang HW, Zhao L, He LC, Sun HP, You QD, Li ZY, Guo QL. Chen FH, et al. Mol Pharmacol. 2012 Nov;82(5):958-71. doi: 10.1124/mol.112.079848. Epub 2012 Aug 21. Mol Pharmacol. 2012. PMID: 22909797

9

Studies on chemical-structure modification and structure-activity relationship of gambogic acid derivatives at carbon(34).

Zhang XJ, Li X, Yang YR, Sun HP, Gao Y, Zhang L, Wang JX, Guo QL, You QD. Zhang XJ, et al. Chem Biodivers. 2012 Oct;9(10):2295-308. doi: 10.1002/cbdv.201200081. Chem Biodivers. 2012. PMID: 23081928

10

Pharmacophore-based drug design and biological evaluation of novel ABCB1 inhibitors.

Zhang SL, Wei YX, Li Q, Sun HP, Peng H, You QD. Zhang SL, et al. Among authors: you qd. Chem Biol Drug Des. 2013 Mar;81(3):349-58. doi: 10.1111/cbdd.12081. Epub 2012 Dec 26. Chem Biol Drug Des. 2013. PMID: 23095256

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