Wu Y - Search Results

1

Affinity-Based Fluorescence Polarization Assay for High-Throughput Screening of Prolyl Hydroxylase 2 Inhibitors.

Lei Y, Hu T, Wu X, Wu Y, Bao Q, Zhang L, Xia H, Sun H, You Q, Zhang X. Lei Y, et al. Among authors: wu y, wu x. ACS Med Chem Lett. 2015 Nov 9;6(12):1236-40. doi: 10.1021/acsmedchemlett.5b00394. eCollection 2015 Dec 10. ACS Med Chem Lett. 2015. PMID: 26713111 Free PMC article.

2

Novel natural-product-like caged xanthones with improved druglike properties and in vivo antitumor potency.

Wu Y, Hu M, Yang L, Li X, Bian J, Jiang F, Sun H, You Q, Zhang X. Wu Y, et al. Bioorg Med Chem Lett. 2015 Jun 15;25(12):2584-8. doi: 10.1016/j.bmcl.2015.04.031. Epub 2015 Apr 18. Bioorg Med Chem Lett. 2015. PMID: 25958244

3

Current Development of ROS-Modulating Agents as Novel Antitumor Therapy.

Wang N, Wu Y, Bian J, Qian X, Lin H, Sun H, You Q, Zhang X. Wang N, et al. Among authors: wu y. Curr Cancer Drug Targets. 2017;17(2):122-136. doi: 10.2174/1568009616666160216125833. Curr Cancer Drug Targets. 2017. PMID: 26881931 Review.

4

Structure-activity relationship of Garcinia xanthones analogues: Potent Hsp90 inhibitors with cytotoxicity and antiangiogenesis activity.

Xu X, Wu Y, Hu M, Li X, Gu C, You Q, Zhang X. Xu X, et al. Among authors: wu y. Bioorg Med Chem. 2016 Oct 1;24(19):4626-4635. doi: 10.1016/j.bmc.2016.07.067. Epub 2016 Aug 1. Bioorg Med Chem. 2016. PMID: 27527413

5

Novel Natural Product-like Caged Xanthones Bearing a Carbamate Moiety Exhibit Antitumor Potency and Anti-Angiogenesis Activity In vivo.

Xu X, Wu Y, Hu M, Li X, Bao Q, Bian J, You Q, Zhang X. Xu X, et al. Among authors: wu y. Sci Rep. 2016 Oct 21;6:35771. doi: 10.1038/srep35771. Sci Rep. 2016. PMID: 27767192 Free PMC article.

6

Application of in-vitro screening methods on hypoxia inducible factor prolyl hydroxylase inhibitors.

Wu Y, Jiang Z, You Q, Zhang X. Wu Y, et al. Bioorg Med Chem. 2017 Aug 1;25(15):3891-3899. doi: 10.1016/j.bmc.2017.05.026. Epub 2017 May 13. Bioorg Med Chem. 2017. PMID: 28625716 Review.

7

'Click Chemistry' Synthesis of Novel Natural Product-Like Caged Xanthones Bearing a 1,2,3-Triazole Moiety with Improved Druglike Properties as Orally Active Antitumor Agents.

Li X, Wu Y, Wang Y, You Q, Zhang X. Li X, et al. Among authors: wu y. Molecules. 2017 Oct 27;22(11):1834. doi: 10.3390/molecules22111834. Molecules. 2017. PMID: 29077076 Free PMC article.

8

Identification by shape-based virtual screening and evaluation of new tyrosinase inhibitors.

Li Q, Yang H, Mo J, Chen Y, Wu Y, Kang C, Sun Y, Sun H. Li Q, et al. Among authors: wu y. PeerJ. 2018 Jan 26;6:e4206. doi: 10.7717/peerj.4206. eCollection 2018. PeerJ. 2018. PMID: 29383286 Free PMC article.

9

An NAD(P)H:Quinone Oxidoreductase 1 Responsive and Self-Immolative Prodrug of 5-Fluorouracil for Safe and Effective Cancer Therapy.

Zhang X, Li X, Li Z, Wu X, Wu Y, You Q, Zhang X. Zhang X, et al. Among authors: wu y, wu x. Org Lett. 2018 Jun 15;20(12):3635-3638. doi: 10.1021/acs.orglett.8b01409. Epub 2018 May 31. Org Lett. 2018. PMID: 29847952

10

Click Chemistry-Based Discovery of [3-Hydroxy-5-(1 H-1,2,3-triazol-4-yl)picolinoyl]glycines as Orally Active Hypoxia-Inducing Factor Prolyl Hydroxylase Inhibitors with Favorable Safety Profiles for the Treatment of Anemia.

Wu Y, Jiang Z, Li Z, Gu J, You Q, Zhang X. Wu Y, et al. J Med Chem. 2018 Jun 28;61(12):5332-5349. doi: 10.1021/acs.jmedchem.8b00549. Epub 2018 Jun 12. J Med Chem. 2018. PMID: 29856623

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