Wu X - Search Results

1

Affinity-Based Fluorescence Polarization Assay for High-Throughput Screening of Prolyl Hydroxylase 2 Inhibitors.

Lei Y, Hu T, Wu X, Wu Y, Bao Q, Zhang L, Xia H, Sun H, You Q, Zhang X. Lei Y, et al. Among authors: wu y, wu x. ACS Med Chem Lett. 2015 Nov 9;6(12):1236-40. doi: 10.1021/acsmedchemlett.5b00394. eCollection 2015 Dec 10. ACS Med Chem Lett. 2015. PMID: 26713111 Free PMC article.

2

Discovery of quinone-directed antitumor agents selectively bioactivated by NQO1 over CPR with improved safety profile.

Bian J, Li X, Wang N, Wu X, You Q, Zhang X. Bian J, et al. Among authors: wu x. Eur J Med Chem. 2017 Mar 31;129:27-40. doi: 10.1016/j.ejmech.2017.02.004. Epub 2017 Feb 6. Eur J Med Chem. 2017. PMID: 28214631

3

2-Substituted 3,7,8-trimethylnaphtho[1,2-b]furan-4,5-diones as specific L-shaped NQO1-mediated redox modulators for the treatment of non-small cell lung cancer.

Zhang X, Bian J, Li X, Wu X, Dong Y, You Q. Zhang X, et al. Among authors: wu x. Eur J Med Chem. 2017 Sep 29;138:616-629. doi: 10.1016/j.ejmech.2017.06.028. Epub 2017 Jun 15. Eur J Med Chem. 2017. PMID: 28710963

4

An NAD(P)H:Quinone Oxidoreductase 1 Responsive and Self-Immolative Prodrug of 5-Fluorouracil for Safe and Effective Cancer Therapy.

Zhang X, Li X, Li Z, Wu X, Wu Y, You Q, Zhang X. Zhang X, et al. Among authors: wu y, wu x. Org Lett. 2018 Jun 15;20(12):3635-3638. doi: 10.1021/acs.orglett.8b01409. Epub 2018 May 31. Org Lett. 2018. PMID: 29847952

5

Discovery of Nonquinone Substrates for NAD(P)H: Quinone Oxidoreductase 1 (NQO1) as Effective Intracellular ROS Generators for the Treatment of Drug-Resistant Non-Small-Cell Lung Cancer.

Wu X, Li X, Li Z, Yu Y, You Q, Zhang X. Wu X, et al. J Med Chem. 2018 Dec 27;61(24):11280-11297. doi: 10.1021/acs.jmedchem.8b01424. Epub 2018 Dec 10. J Med Chem. 2018. PMID: 30508483

6

A Carbon-Carbon Bond Cleavage-Based Prodrug Activation Strategy Applied to β-Lapachone for Cancer-Specific Targeting.

Gong Q, Li X, Li T, Wu X, Hu J, Yang F, Zhang X. Gong Q, et al. Among authors: wu x. Angew Chem Int Ed Engl. 2022 Oct 4;61(40):e202210001. doi: 10.1002/anie.202210001. Epub 2022 Aug 23. Angew Chem Int Ed Engl. 2022. PMID: 35938884

7

Association between the changes in the estimated glucose disposal rate and new-onset cardiovascular disease in middle-aged and elderly individuals: A nationwide prospective cohort study in China.

Yan L, Zhou Z, Wu X, Qiu Y, Liu Z, Luo L, Yang Y, Lu X, He J, Xia W. Yan L, et al. Among authors: wu x. Diabetes Obes Metab. 2025 Jan 6. doi: 10.1111/dom.16179. Online ahead of print. Diabetes Obes Metab. 2025. PMID: 39762991

8

Helicobacter pylori infection promotes M1 macrophage polarization and gastric inflammation by activation of NLRP3 inflammasome via TNF/TNFR1 axis.

Fei X, Chen S, Li L, Xu X, Wang H, Ke H, He C, Xie C, Wu X, Liu J, Xie Y, Lu N, Zhu Y, Li N. Fei X, et al. Among authors: wu x. Cell Commun Signal. 2025 Jan 6;23(1):6. doi: 10.1186/s12964-024-02017-7. Cell Commun Signal. 2025. PMID: 39762835

9

MAIT cells modulating the oral lichen planus immune microenvironment: a cellular crosstalk perspective.

Mi Q, Wu X, Chen Y, Meng W. Mi Q, et al. Among authors: wu x. Inflamm Res. 2025 Jan 7;74(1):10. doi: 10.1007/s00011-024-01990-6. Inflamm Res. 2025. PMID: 39762617 Review.

10

Development of nucleus-targeted histone-tail-based photoaffinity probes to profile the epigenetic interactome in native cells.

Wang Y, Fan J, Meng X, Shu Q, Wu Y, Chu GC, Ji R, Ye Y, Wu X, Shi J, Deng H, Liu L, Li YM. Wang Y, et al. Among authors: wu x. Nat Commun. 2025 Jan 6;16(1):415. doi: 10.1038/s41467-024-55046-8. Nat Commun. 2025. PMID: 39762271

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