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Assessing the Mitochondrial Membrane Potential in Cells and In Vivo using Targeted Click Chemistry and Mass Spectrometry.
Logan A, Pell VR, Shaffer KJ, Evans C, Stanley NJ, Robb EL, Prime TA, Chouchani ET, Cochemé HM, Fearnley IM, Vidoni S, James AM, Porteous CM, Partridge L, Krieg T, Smith RA, Murphy MP. Logan A, et al. Among authors: smith ra. Cell Metab. 2016 Feb 9;23(2):379-85. doi: 10.1016/j.cmet.2015.11.014. Epub 2015 Dec 17. Cell Metab. 2016. PMID: 26712463 Free PMC article.
Measurement of H2O2 within living Drosophila during aging using a ratiometric mass spectrometry probe targeted to the mitochondrial matrix.
Cochemé HM, Quin C, McQuaker SJ, Cabreiro F, Logan A, Prime TA, Abakumova I, Patel JV, Fearnley IM, James AM, Porteous CM, Smith RA, Saeed S, Carré JE, Singer M, Gems D, Hartley RC, Partridge L, Murphy MP. Cochemé HM, et al. Among authors: smith ra. Cell Metab. 2011 Mar 2;13(3):340-50. doi: 10.1016/j.cmet.2011.02.003. Cell Metab. 2011. PMID: 21356523 Free PMC article.
A mitochondria-targeted mass spectrometry probe to detect glyoxals: implications for diabetes.
Pun PB, Logan A, Darley-Usmar V, Chacko B, Johnson MS, Huang GW, Rogatti S, Prime TA, Methner C, Krieg T, Fearnley IM, Larsen L, Larsen DS, Menger KE, Collins Y, James AM, Kumar GD, Hartley RC, Smith RA, Murphy MP. Pun PB, et al. Among authors: smith ra. Free Radic Biol Med. 2014 Feb;67(100):437-50. doi: 10.1016/j.freeradbiomed.2013.11.025. Epub 2013 Dec 4. Free Radic Biol Med. 2014. PMID: 24316194 Free PMC article.
A mitochondria-targeted S-nitrosothiol modulates respiration, nitrosates thiols, and protects against ischemia-reperfusion injury.
Prime TA, Blaikie FH, Evans C, Nadtochiy SM, James AM, Dahm CC, Vitturi DA, Patel RP, Hiley CR, Abakumova I, Requejo R, Chouchani ET, Hurd TR, Garvey JF, Taylor CT, Brookes PS, Smith RA, Murphy MP. Prime TA, et al. Among authors: smith ra. Proc Natl Acad Sci U S A. 2009 Jun 30;106(26):10764-9. doi: 10.1073/pnas.0903250106. Epub 2009 Jun 15. Proc Natl Acad Sci U S A. 2009. PMID: 19528654 Free PMC article.
Delivery of bioactive molecules to mitochondria in vivo.
Smith RA, Porteous CM, Gane AM, Murphy MP. Smith RA, et al. Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5407-12. doi: 10.1073/pnas.0931245100. Epub 2003 Apr 15. Proc Natl Acad Sci U S A. 2003. PMID: 12697897 Free PMC article.
1,951 results