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The structure-dependent toxicity, pharmacokinetics and anti-tumour activity of HPMA copolymer conjugates in the treatment of solid tumours and leukaemia.
Tomalova B, Sirova M, Rossmann P, Pola R, Strohalm J, Chytil P, Cerny V, Tomala J, Kabesova M, Rihova B, Ulbrich K, Etrych T, Kovar M. Tomalova B, et al. Among authors: kovar m. J Control Release. 2016 Feb 10;223:1-10. doi: 10.1016/j.jconrel.2015.12.023. Epub 2015 Dec 18. J Control Release. 2016. PMID: 26708020
Antiproliferative effect of a lectin- and anti-Thy-1.2 antibody-targeted HPMA copolymer-bound doxorubicin on primary and metastatic human colorectal carcinoma and on human colorectal carcinoma transfected with the mouse Thy-1.2 gene.
Ríhová B, Jelínková M, Strohalm J, St'astný M, Hovorka O, Plocová D, Kovár M, Dráberová L, Ulbrich K. Ríhová B, et al. Among authors: kovar m. Bioconjug Chem. 2000 Sep-Oct;11(5):664-73. doi: 10.1021/bc9901696. Bioconjug Chem. 2000. PMID: 10995209
Drug-HPMA-HuIg conjugates effective against human solid cancer.
Ríhová B, Strohalm J, Kubácková K, Jelínková M, Rozprimová L, Sírová M, Plocová D, Mrkvan T, Kovár M, Pokorná J, Etrych T, Ulbrich K. Ríhová B, et al. Among authors: kovar m. Adv Exp Med Biol. 2003;519:125-43. doi: 10.1007/0-306-47932-x_8. Adv Exp Med Biol. 2003. PMID: 12675212 Review. No abstract available.
186 results