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A high-resolution gene expression atlas of epistasis between gene-specific transcription factors exposes potential mechanisms for genetic interactions.
Sameith K, Amini S, Groot Koerkamp MJ, van Leenen D, Brok M, Brabers N, Lijnzaad P, van Hooff SR, Benschop JJ, Lenstra TL, Apweiler E, van Wageningen S, Snel B, Holstege FC, Kemmeren P. Sameith K, et al. Among authors: van wageningen s. BMC Biol. 2015 Dec 23;13:112. doi: 10.1186/s12915-015-0222-5. BMC Biol. 2015. PMID: 26700642 Free PMC article.
Functional overlap and regulatory links shape genetic interactions between signaling pathways.
van Wageningen S, Kemmeren P, Lijnzaad P, Margaritis T, Benschop JJ, de Castro IJ, van Leenen D, Groot Koerkamp MJ, Ko CW, Miles AJ, Brabers N, Brok MO, Lenstra TL, Fiedler D, Fokkens L, Aldecoa R, Apweiler E, Taliadouros V, Sameith K, van de Pasch LA, van Hooff SR, Bakker LV, Krogan NJ, Snel B, Holstege FC. van Wageningen S, et al. Cell. 2010 Dec 10;143(6):991-1004. doi: 10.1016/j.cell.2010.11.021. Cell. 2010. PMID: 21145464 Free PMC article.
Large-scale genetic perturbations reveal regulatory networks and an abundance of gene-specific repressors.
Kemmeren P, Sameith K, van de Pasch LA, Benschop JJ, Lenstra TL, Margaritis T, O'Duibhir E, Apweiler E, van Wageningen S, Ko CW, van Heesch S, Kashani MM, Ampatziadis-Michailidis G, Brok MO, Brabers NA, Miles AJ, Bouwmeester D, van Hooff SR, van Bakel H, Sluiters E, Bakker LV, Snel B, Lijnzaad P, van Leenen D, Groot Koerkamp MJ, Holstege FC. Kemmeren P, et al. Among authors: van wageningen s. Cell. 2014 Apr 24;157(3):740-52. doi: 10.1016/j.cell.2014.02.054. Cell. 2014. PMID: 24766815 Free article.
Functional organization of the S. cerevisiae phosphorylation network.
Fiedler D, Braberg H, Mehta M, Chechik G, Cagney G, Mukherjee P, Silva AC, Shales M, Collins SR, van Wageningen S, Kemmeren P, Holstege FC, Weissman JS, Keogh MC, Koller D, Shokat KM, Krogan NJ. Fiedler D, et al. Among authors: van wageningen s. Cell. 2009 Mar 6;136(5):952-63. doi: 10.1016/j.cell.2008.12.039. Cell. 2009. PMID: 19269370 Free PMC article.
Structure-system correlation identifies a gene regulatory Mediator submodule.
Larivière L, Seizl M, van Wageningen S, Röther S, van de Pasch L, Feldmann H, Strässer K, Hahn S, Holstege FC, Cramer P. Larivière L, et al. Among authors: van wageningen s, van de pasch l. Genes Dev. 2008 Apr 1;22(7):872-7. doi: 10.1101/gad.465108. Genes Dev. 2008. PMID: 18381891 Free PMC article.
15 results