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An ancestral host defence peptide within human β-defensin 3 recapitulates the antibacterial and antiviral activity of the full-length molecule.
Nigro E, Colavita I, Sarnataro D, Scudiero O, Zambrano G, Granata V, Daniele A, Carotenuto A, Galdiero S, Folliero V, Galdiero M, Urbanowicz RA, Ball JK, Salvatore F, Pessi A. Nigro E, et al. Among authors: pessi a. Sci Rep. 2015 Dec 21;5:18450. doi: 10.1038/srep18450. Sci Rep. 2015. PMID: 26688341 Free PMC article.
Design and activity of a cyclic mini-β-defensin analog: a novel antimicrobial tool.
Scudiero O, Nigro E, Cantisani M, Colavita I, Leone M, Mercurio FA, Galdiero M, Pessi A, Daniele A, Salvatore F, Galdiero S. Scudiero O, et al. Among authors: pessi a. Int J Nanomedicine. 2015 Oct 15;10:6523-39. doi: 10.2147/IJN.S89610. eCollection 2015. Int J Nanomedicine. 2015. PMID: 26508857 Free PMC article.
A first-in-human study of the novel HIV-fusion inhibitor C34-PEG4-Chol.
Quinn K, Traboni C, Penchala SD, Bouliotis G, Doyle N, Libri V, Khoo S, Ashby D, Weber J, Nicosia A, Cortese R, Pessi A, Winston A. Quinn K, et al. Among authors: pessi a. Sci Rep. 2017 Aug 25;7(1):9447. doi: 10.1038/s41598-017-09230-0. Sci Rep. 2017. PMID: 28842581 Free PMC article. Clinical Trial.
142 results