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Mice with Shank3 Mutations Associated with ASD and Schizophrenia Display Both Shared and Distinct Defects.
Zhou Y, Kaiser T, Monteiro P, Zhang X, Van der Goes MS, Wang D, Barak B, Zeng M, Li C, Lu C, Wells M, Amaya A, Nguyen S, Lewis M, Sanjana N, Zhou Y, Zhang M, Zhang F, Fu Z, Feng G. Zhou Y, et al. Among authors: sanjana n. Neuron. 2016 Jan 6;89(1):147-62. doi: 10.1016/j.neuron.2015.11.023. Epub 2015 Dec 10. Neuron. 2016. PMID: 26687841 Free PMC article.
Discovery of target genes and pathways at GWAS loci by pooled single-cell CRISPR screens.
Morris JA, Caragine C, Daniloski Z, Domingo J, Barry T, Lu L, Davis K, Ziosi M, Glinos DA, Hao S, Mimitou EP, Smibert P, Roeder K, Katsevich E, Lappalainen T, Sanjana NE. Morris JA, et al. Science. 2023 May 19;380(6646):eadh7699. doi: 10.1126/science.adh7699. Epub 2023 May 19. Science. 2023. PMID: 37141313 Free PMC article.
Low copy CRISPR-Cas13d mitigates collateral RNA cleavage.
Hart SK, Wessels HH, Méndez-Mancilla A, Müller S, Drabavicius G, Choi O, Sanjana NE. Hart SK, et al. Among authors: sanjana ne. bioRxiv [Preprint]. 2024 May 14:2024.05.13.594039. doi: 10.1101/2024.05.13.594039. bioRxiv. 2024. PMID: 38798586 Free PMC article. Preprint.
Genome-wide CRISPR screens in spheroid culture reveal that the tumor suppressor LKB1 inhibits growth via the PIKFYVE lipid kinase.
Ferrarone JR, Thomas J, Unni AM, Zheng Y, Nagiec MJ, Gardner EE, Mashadova O, Li K, Koundouros N, Montalbano A, Mustafa M, Cantley LC, Blenis J, Sanjana NE, Varmus H. Ferrarone JR, et al. Among authors: sanjana ne. Proc Natl Acad Sci U S A. 2024 May 21;121(21):e2403685121. doi: 10.1073/pnas.2403685121. Epub 2024 May 14. Proc Natl Acad Sci U S A. 2024. PMID: 38743625 Free PMC article.
85 results