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Targeting the MAPK7/MMP9 axis for metastasis in primary bone cancer.
Green D, Eyre H, Singh A, Taylor JT, Chu J, Jeys L, Sumathi V, Coonar A, Rassl D, Babur M, Forster D, Alzabin S, Ponthan F, McMahon A, Bigger B, Reekie T, Kassiou M, Williams K, Dalmay T, Fraser WD, Finegan KG. Green D, et al. Among authors: finegan kg. Oncogene. 2020 Aug;39(33):5553-5569. doi: 10.1038/s41388-020-1379-0. Epub 2020 Jul 13. Oncogene. 2020. PMID: 32655131 Free PMC article.
Inhibiting ERK5 overcomes breast cancer resistance to anti-HER2 therapy by targeting the G1/S cell cycle transition.
Zhang J, Pearson AJ, Sabherwal N, Telfer BA, Ali N, Kan K, Xu Q, Zhang W, Chen F, Li S, Wang J, Gray NS, Risa-Ebrí B, Finegan KG, Cross MJ, Giurisato E, Whitmarsh AJ, Tournier C. Zhang J, et al. Among authors: finegan kg. Cancer Res Commun. 2022 Mar 10;2(3):131-145. doi: 10.1158/2767-9764.CRC-21-0089. Cancer Res Commun. 2022. PMID: 36466034 Free PMC article.
ERK5 is a critical mediator of inflammation-driven cancer.
Finegan KG, Perez-Madrigal D, Hitchin JR, Davies CC, Jordan AM, Tournier C. Finegan KG, et al. Cancer Res. 2015 Feb 15;75(4):742-53. doi: 10.1158/0008-5472.CAN-13-3043. Epub 2015 Feb 3. Cancer Res. 2015. PMID: 25649771 Free PMC article.
Extracellular-Regulated Protein Kinase 5-Mediated Control of p21 Expression Promotes Macrophage Proliferation Associated with Tumor Growth and Metastasis.
Giurisato E, Lonardi S, Telfer B, Lussoso S, Risa-Ebrí B, Zhang J, Russo I, Wang J, Santucci A, Finegan KG, Gray NS, Vermi W, Tournier C. Giurisato E, et al. Among authors: finegan kg. Cancer Res. 2020 Aug 15;80(16):3319-3330. doi: 10.1158/0008-5472.CAN-19-2416. Epub 2020 Jun 19. Cancer Res. 2020. PMID: 32561530 Free PMC article.
Targeted deletion of mek5 causes early embryonic death and defects in the extracellular signal-regulated kinase 5/myocyte enhancer factor 2 cell survival pathway.
Wang X, Merritt AJ, Seyfried J, Guo C, Papadakis ES, Finegan KG, Kayahara M, Dixon J, Boot-Handford RP, Cartwright EJ, Mayer U, Tournier C. Wang X, et al. Among authors: finegan kg. Mol Cell Biol. 2005 Jan;25(1):336-45. doi: 10.1128/MCB.25.1.336-345.2005. Mol Cell Biol. 2005. PMID: 15601854 Free PMC article.
17 results