Tyner JW - Search Results

1

What's different about atypical CML and chronic neutrophilic leukemia?

Dao KH, Tyner JW. Dao KH, et al. Among authors: tyner jw. Hematology Am Soc Hematol Educ Program. 2015;2015:264-71. doi: 10.1182/asheducation-2015.1.264. Hematology Am Soc Hematol Educ Program. 2015. PMID: 26637732 Free PMC article. Review.

2

Next-generation medicine: combining BCR-ABL and Hedgehog-targeted therapies.

Dao KH, Tyner JW. Dao KH, et al. Among authors: tyner jw. Clin Cancer Res. 2013 Mar 15;19(6):1309-11. doi: 10.1158/1078-0432.CCR-12-3934. Epub 2013 Feb 4. Clin Cancer Res. 2013. PMID: 23382113 Free PMC article.

3

Oncogenic CSF3R mutations in chronic neutrophilic leukemia and atypical CML.

Maxson JE, Gotlib J, Pollyea DA, Fleischman AG, Agarwal A, Eide CA, Bottomly D, Wilmot B, McWeeney SK, Tognon CE, Pond JB, Collins RH, Goueli B, Oh ST, Deininger MW, Chang BH, Loriaux MM, Druker BJ, Tyner JW. Maxson JE, et al. Among authors: tyner jw. N Engl J Med. 2013 May 9;368(19):1781-90. doi: 10.1056/NEJMoa1214514. N Engl J Med. 2013. PMID: 23656643 Free PMC article.

4

The PI3K/Akt1 pathway enhances steady-state levels of FANCL.

Dao KH, Rotelli MD, Brown BR, Yates JE, Rantala J, Tognon C, Tyner JW, Druker BJ, Bagby GC. Dao KH, et al. Among authors: tyner jw. Mol Biol Cell. 2013 Aug;24(16):2582-92. doi: 10.1091/mbc.E13-03-0144. Epub 2013 Jun 19. Mol Biol Cell. 2013. PMID: 23783032 Free PMC article.

5

The new genetics of chronic neutrophilic leukemia and atypical CML: implications for diagnosis and treatment.

Gotlib J, Maxson JE, George TI, Tyner JW. Gotlib J, et al. Among authors: tyner jw. Blood. 2013 Sep 5;122(10):1707-11. doi: 10.1182/blood-2013-05-500959. Epub 2013 Jul 29. Blood. 2013. PMID: 23896413 Free PMC article. Review.

6

The CSF3R T618I mutation causes a lethal neutrophilic neoplasia in mice that is responsive to therapeutic JAK inhibition.

Fleischman AG, Maxson JE, Luty SB, Agarwal A, Royer LR, Abel ML, MacManiman JD, Loriaux MM, Druker BJ, Tyner JW. Fleischman AG, et al. Among authors: tyner jw. Blood. 2013 Nov 21;122(22):3628-31. doi: 10.1182/blood-2013-06-509976. Epub 2013 Sep 30. Blood. 2013. PMID: 24081659 Free PMC article.

7

Ligand independence of the T618I mutation in the colony-stimulating factor 3 receptor (CSF3R) protein results from loss of O-linked glycosylation and increased receptor dimerization.

Maxson JE, Luty SB, MacManiman JD, Abel ML, Druker BJ, Tyner JW. Maxson JE, et al. Among authors: tyner jw. J Biol Chem. 2014 Feb 28;289(9):5820-7. doi: 10.1074/jbc.M113.508440. Epub 2014 Jan 8. J Biol Chem. 2014. PMID: 24403076 Free PMC article.

8

Significant clinical response to JAK1/2 inhibition in a patient with CSF3R-T618I-positive atypical chronic myeloid leukemia.

Dao KH, Solti MB, Maxson JE, Winton EF, Press RD, Druker BJ, Tyner JW. Dao KH, et al. Among authors: tyner jw. Leuk Res Rep. 2014 Aug 1;3(2):67-9. doi: 10.1016/j.lrr.2014.07.002. eCollection 2014. Leuk Res Rep. 2014. PMID: 25180155 Free PMC article.

9

The Colony-Stimulating Factor 3 Receptor T640N Mutation Is Oncogenic, Sensitive to JAK Inhibition, and Mimics T618I.

Maxson JE, Luty SB, MacManiman JD, Paik JC, Gotlib J, Greenberg P, Bahamadi S, Savage SL, Abel ML, Eide CA, Loriaux MM, Stevens EA, Tyner JW. Maxson JE, et al. Among authors: tyner jw. Clin Cancer Res. 2016 Feb 1;22(3):757-64. doi: 10.1158/1078-0432.CCR-14-3100. Epub 2015 Oct 16. Clin Cancer Res. 2016. PMID: 26475333 Free PMC article.

10

Mutant calreticulin-expressing cells induce monocyte hyperreactivity through a paracrine mechanism.

Garbati MR, Welgan CA, Landefeld SH, Newell LF, Agarwal A, Dunlap JB, Chourasia TK, Lee H, Elferich J, Traer E, Rattray R, Cascio MJ, Press RD, Bagby GC, Tyner JW, Druker BJ, Dao KH. Garbati MR, et al. Among authors: tyner jw. Am J Hematol. 2016 Feb;91(2):211-9. doi: 10.1002/ajh.24245. Am J Hematol. 2016. PMID: 26573090 Free PMC article.

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