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Targeting MYCN-Driven Transcription By BET-Bromodomain Inhibition.
Henssen A, Althoff K, Odersky A, Beckers A, Koche R, Speleman F, Schäfers S, Bell E, Nortmeyer M, Westermann F, De Preter K, Florin A, Heukamp L, Spruessel A, Astrahanseff K, Lindner S, Sadowski N, Schramm A, Astorgues-Xerri L, Riveiro ME, Eggert A, Cvitkovic E, Schulte JH. Henssen A, et al. Among authors: heukamp l. Clin Cancer Res. 2016 May 15;22(10):2470-81. doi: 10.1158/1078-0432.CCR-15-1449. Epub 2015 Dec 2. Clin Cancer Res. 2016. PMID: 26631615
MYCN regulates oncogenic MicroRNAs in neuroblastoma.
Schulte JH, Horn S, Otto T, Samans B, Heukamp LC, Eilers UC, Krause M, Astrahantseff K, Klein-Hitpass L, Buettner R, Schramm A, Christiansen H, Eilers M, Eggert A, Berwanger B. Schulte JH, et al. Among authors: heukamp lc. Int J Cancer. 2008 Feb 1;122(3):699-704. doi: 10.1002/ijc.23153. Int J Cancer. 2008. PMID: 17943719
MicroRNAs in the pathogenesis of neuroblastoma.
Schulte JH, Horn S, Schlierf S, Schramm A, Heukamp LC, Christiansen H, Buettner R, Berwanger B, Eggert A. Schulte JH, et al. Cancer Lett. 2009 Feb 8;274(1):10-5. doi: 10.1016/j.canlet.2008.06.010. Epub 2008 Jul 17. Cancer Lett. 2009. PMID: 18639376 Review.
Insulin-like growth factor-1 receptor acts as a growth regulator in synovial sarcoma.
Friedrichs N, Küchler J, Endl E, Koch A, Czerwitzki J, Wurst P, Metzger D, Schulte JH, Holst MI, Heukamp LC, Larsson O, Tanaka S, Kawai A, Wardelmann E, Buettner R, Pietsch T, Hartmann W. Friedrichs N, et al. Among authors: heukamp lc. J Pathol. 2008 Dec;216(4):428-39. doi: 10.1002/path.2438. J Pathol. 2008. PMID: 18855347
Lysine-specific demethylase 1 restricts hematopoietic progenitor proliferation and is essential for terminal differentiation.
Sprüssel A, Schulte JH, Weber S, Necke M, Händschke K, Thor T, Pajtler KW, Schramm A, König K, Diehl L, Mestdagh P, Vandesompele J, Speleman F, Jastrow H, Heukamp LC, Schüle R, Dührsen U, Buettner R, Eggert A, Göthert JR. Sprüssel A, et al. Among authors: heukamp lc. Leukemia. 2012 Sep;26(9):2039-51. doi: 10.1038/leu.2012.157. Epub 2012 Jun 13. Leukemia. 2012. PMID: 22699452
Targeted expression of mutated ALK induces neuroblastoma in transgenic mice.
Heukamp LC, Thor T, Schramm A, De Preter K, Kumps C, De Wilde B, Odersky A, Peifer M, Lindner S, Spruessel A, Pattyn F, Mestdagh P, Menten B, Kuhfittig-Kulle S, Künkele A, König K, Meder L, Chatterjee S, Ullrich RT, Schulte S, Vandesompele J, Speleman F, Büttner R, Eggert A, Schulte JH. Heukamp LC, et al. Sci Transl Med. 2012 Jul 4;4(141):141ra91. doi: 10.1126/scitranslmed.3003967. Sci Transl Med. 2012. PMID: 22764207
183 results