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SLC46A3 Is Required to Transport Catabolites of Noncleavable Antibody Maytansine Conjugates from the Lysosome to the Cytoplasm.
Hamblett KJ, Jacob AP, Gurgel JL, Tometsko ME, Rock BM, Patel SK, Milburn RR, Siu S, Ragan SP, Rock DA, Borths CJ, O'Neill JW, Chang WS, Weidner MF, Bio MM, Quon KC, Fanslow WC. Hamblett KJ, et al. Among authors: borths cj. Cancer Res. 2015 Dec 15;75(24):5329-40. doi: 10.1158/0008-5472.CAN-15-1610. Epub 2015 Dec 2. Cancer Res. 2015. PMID: 26631267
Telescoped Process to Manufacture 6,6,6-Trifluorofucose via Diastereoselective Transfer Hydrogenation: Scalable Access to an Inhibitor of Fucosylation Utilized in Monoclonal Antibody Production.
Achmatowicz MM, Allen JG, Bio MM, Bartberger MD, Borths CJ, Colyer JT, Crockett RD, Hwang TL, Koek JN, Osgood SA, Roberts SW, Swietlow A, Thiel OR, Caille S. Achmatowicz MM, et al. Among authors: borths cj. J Org Chem. 2016 Jun 3;81(11):4736-43. doi: 10.1021/acs.joc.6b00646. Epub 2016 May 20. J Org Chem. 2016. PMID: 27152753