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Natural selection shaped regional mtDNA variation in humans.
Mishmar D, Ruiz-Pesini E, Golik P, Macaulay V, Clark AG, Hosseini S, Brandon M, Easley K, Chen E, Brown MD, Sukernik RI, Olckers A, Wallace DC. Mishmar D, et al. Among authors: wallace dc. Proc Natl Acad Sci U S A. 2003 Jan 7;100(1):171-6. doi: 10.1073/pnas.0136972100. Epub 2002 Dec 30. Proc Natl Acad Sci U S A. 2003. PMID: 12509511 Free PMC article.
Mouse mtDNA mutant model of Leber hereditary optic neuropathy.
Lin CS, Sharpley MS, Fan W, Waymire KG, Sadun AA, Carelli V, Ross-Cisneros FN, Baciu P, Sung E, McManus MJ, Pan BX, Gil DW, Macgregor GR, Wallace DC. Lin CS, et al. Among authors: wallace dc. Proc Natl Acad Sci U S A. 2012 Dec 4;109(49):20065-70. doi: 10.1073/pnas.1217113109. Epub 2012 Nov 5. Proc Natl Acad Sci U S A. 2012. PMID: 23129651 Free PMC article.
Severity of cardiomyopathy associated with adenine nucleotide translocator-1 deficiency correlates with mtDNA haplogroup.
Strauss KA, DuBiner L, Simon M, Zaragoza M, Sengupta PP, Li P, Narula N, Dreike S, Platt J, Procaccio V, Ortiz-González XR, Puffenberger EG, Kelley RI, Morton DH, Narula J, Wallace DC. Strauss KA, et al. Among authors: wallace dc. Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3453-8. doi: 10.1073/pnas.1300690110. Epub 2013 Feb 11. Proc Natl Acad Sci U S A. 2013. PMID: 23401503 Free PMC article.
Progressive increase in mtDNA 3243A>G heteroplasmy causes abrupt transcriptional reprogramming.
Picard M, Zhang J, Hancock S, Derbeneva O, Golhar R, Golik P, O'Hearn S, Levy S, Potluri P, Lvova M, Davila A, Lin CS, Perin JC, Rappaport EF, Hakonarson H, Trounce IA, Procaccio V, Wallace DC. Picard M, et al. Among authors: wallace dc. Proc Natl Acad Sci U S A. 2014 Sep 23;111(38):E4033-42. doi: 10.1073/pnas.1414028111. Epub 2014 Sep 5. Proc Natl Acad Sci U S A. 2014. PMID: 25192935 Free PMC article.
561 results