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Page 1
Transcriptomics and the mechanisms of antidepressant efficacy.
Hodgson K, Tansey KE, Powell TR, Coppola G, Uher R, Zvezdana Dernovšek M, Mors O, Hauser J, Souery D, Maier W, Henigsberg N, Rietschel M, Placentino A, Aitchison KJ, Craig IW, Farmer AE, Breen G, McGuffin P, Dobson R. Hodgson K, et al. Among authors: dobson r. Eur Neuropsychopharmacol. 2016 Jan;26(1):105-112. doi: 10.1016/j.euroneuro.2015.10.009. Epub 2015 Nov 12. Eur Neuropsychopharmacol. 2016. PMID: 26621261 Clinical Trial.
Mitochondrial dysfunction and immune activation are detectable in early Alzheimer's disease blood.
Lunnon K, Ibrahim Z, Proitsi P, Lourdusamy A, Newhouse S, Sattlecker M, Furney S, Saleem M, Soininen H, Kłoszewska I, Mecocci P, Tsolaki M, Vellas B, Coppola G, Geschwind D, Simmons A, Lovestone S, Dobson R, Hodges A; AddNeuroMed Consortium. Lunnon K, et al. Among authors: dobson r. J Alzheimers Dis. 2012;30(3):685-710. doi: 10.3233/JAD-2012-111592. J Alzheimers Dis. 2012. PMID: 22466004 Free article.
A blood gene expression marker of early Alzheimer's disease.
Lunnon K, Sattlecker M, Furney SJ, Coppola G, Simmons A, Proitsi P, Lupton MK, Lourdusamy A, Johnston C, Soininen H, Kłoszewska I, Mecocci P, Tsolaki M, Vellas B, Geschwind D, Lovestone S, Dobson R, Hodges A; dNeuroMed Consortium. Lunnon K, et al. Among authors: dobson r. J Alzheimers Dis. 2013;33(3):737-53. doi: 10.3233/JAD-2012-121363. J Alzheimers Dis. 2013. PMID: 23042217 Free article.
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis.
Eyre S, Bowes J, Diogo D, Lee A, Barton A, Martin P, Zhernakova A, Stahl E, Viatte S, McAllister K, Amos CI, Padyukov L, Toes RE, Huizinga TW, Wijmenga C, Trynka G, Franke L, Westra HJ, Alfredsson L, Hu X, Sandor C, de Bakker PI, Davila S, Khor CC, Heng KK, Andrews R, Edkins S, Hunt SE, Langford C, Symmons D; Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate; Wellcome Trust Case Control Consortium; Concannon P, Onengut-Gumuscu S, Rich SS, Deloukas P, Gonzalez-Gay MA, Rodriguez-Rodriguez L, Ärlsetig L, Martin J, Rantapää-Dahlqvist S, Plenge RM, Raychaudhuri S, Klareskog L, Gregersen PK, Worthington J. Eyre S, et al. Nat Genet. 2012 Dec;44(12):1336-40. doi: 10.1038/ng.2462. Epub 2012 Nov 11. Nat Genet. 2012. PMID: 23143596 Free PMC article.
Exploring the role of drug-metabolising enzymes in antidepressant side effects.
Hodgson K, Tansey KE, Uher R, Dernovšek MZ, Mors O, Hauser J, Souery D, Maier W, Henigsberg N, Rietschel M, Placentino A, Craig IW, Aitchison KJ, Farmer AE, Dobson RJ, McGuffin P. Hodgson K, et al. Among authors: dobson rj. Psychopharmacology (Berl). 2015 Jul;232(14):2609-17. doi: 10.1007/s00213-015-3898-x. Epub 2015 Mar 12. Psychopharmacology (Berl). 2015. PMID: 25761838 Free PMC article.
Combining clinical variables to optimize prediction of antidepressant treatment outcomes.
Iniesta R, Malki K, Maier W, Rietschel M, Mors O, Hauser J, Henigsberg N, Dernovsek MZ, Souery D, Stahl D, Dobson R, Aitchison KJ, Farmer A, Lewis CM, McGuffin P, Uher R. Iniesta R, et al. Among authors: dobson r. J Psychiatr Res. 2016 Jul;78:94-102. doi: 10.1016/j.jpsychires.2016.03.016. Epub 2016 Apr 1. J Psychiatr Res. 2016. PMID: 27089522 Free article. Clinical Trial.
Immune signatures and disorder-specific patterns in a cross-disorder gene expression analysis.
de Jong S, Newhouse SJ, Patel H, Lee S, Dempster D, Curtis C, Paya-Cano J, Murphy D, Wilson CE, Horder J, Mendez MA, Asherson P, Rivera M, Costello H, Maltezos S, Whitwell S, Pitts M, Tye C, Ashwood KL, Bolton P, Curran S, McGuffin P, Dobson R, Breen G. de Jong S, et al. Among authors: dobson r. Br J Psychiatry. 2016 Sep;209(3):202-8. doi: 10.1192/bjp.bp.115.175471. Epub 2016 May 5. Br J Psychiatry. 2016. PMID: 27151072 Free PMC article.
Antidepressant drug-specific prediction of depression treatment outcomes from genetic and clinical variables.
Iniesta R, Hodgson K, Stahl D, Malki K, Maier W, Rietschel M, Mors O, Hauser J, Henigsberg N, Dernovsek MZ, Souery D, Dobson R, Aitchison KJ, Farmer A, McGuffin P, Lewis CM, Uher R. Iniesta R, et al. Among authors: dobson r. Sci Rep. 2018 Apr 3;8(1):5530. doi: 10.1038/s41598-018-23584-z. Sci Rep. 2018. PMID: 29615645 Free PMC article. Clinical Trial.
Differential gene expression analysis in blood of first episode psychosis patients.
Leirer DJ, Iyegbe CO, Di Forti M, Patel H, Carra E, Fraietta S, Colizzi M, Mondelli V, Quattrone D, Lally J, Ajnakina O, Lee SH, Curtis CJ, Breen G, Pariante C, Aitchison K, Dazzan P, Murray RM, Dobson RJB, Newhouse SJ. Leirer DJ, et al. Schizophr Res. 2019 Jul;209:88-97. doi: 10.1016/j.schres.2019.05.011. Epub 2019 May 19. Schizophr Res. 2019. PMID: 31113746 Free PMC article.
1,287 results