Goyal NS - Search Results

1

Pharmacokinetics, pharmacodynamics and adverse event profile of GSK2256294, a novel soluble epoxide hydrolase inhibitor.

Lazaar AL, Yang L, Boardley RL, Goyal NS, Robertson J, Baldwin SJ, Newby DE, Wilkinson IB, Tal-Singer R, Mayer RJ, Cheriyan J. Lazaar AL, et al. Among authors: goyal ns. Br J Clin Pharmacol. 2016 May;81(5):971-9. doi: 10.1111/bcp.12855. Epub 2016 Jan 17. Br J Clin Pharmacol. 2016. PMID: 26620151 Free PMC article. Clinical Trial.

2

Epithelial desquamation observed in a phase I study of an oral cathepsin C inhibitor (GSK2793660).

Miller BE, Mayer RJ, Goyal N, Bal J, Dallow N, Boyce M, Carpenter D, Churchill A, Heslop T, Lazaar AL. Miller BE, et al. Br J Clin Pharmacol. 2017 Dec;83(12):2813-2820. doi: 10.1111/bcp.13398. Epub 2017 Sep 20. Br J Clin Pharmacol. 2017. PMID: 28800383 Free PMC article. Clinical Trial.

3

Clinical Pharmacokinetics, Safety, and Tolerability of a Novel, First-in-Class TRPV4 Ion Channel Inhibitor, GSK2798745, in Healthy and Heart Failure Subjects.

Goyal N, Skrdla P, Schroyer R, Kumar S, Fernando D, Oughton A, Norton N, Sprecher DL, Cheriyan J. Goyal N, et al. Am J Cardiovasc Drugs. 2019 Jun;19(3):335-342. doi: 10.1007/s40256-018-00320-6. Am J Cardiovasc Drugs. 2019. PMID: 30637626 Clinical Trial.

4

Dose-response modelling of umeclidinium and fluticasone furoate/umeclidinium in asthma.

Yang S, Goyal N, Beerahee M, Trivedi R, Lee L, Pascoe S. Yang S, et al. Eur J Clin Pharmacol. 2015 Sep;71(9):1051-8. doi: 10.1007/s00228-015-1894-z. Epub 2015 Jul 16. Eur J Clin Pharmacol. 2015. PMID: 26174114 Clinical Trial.

5

Pharmacokinetic Interactions between Tafenoquine and Dihydroartemisinin-Piperaquine or Artemether-Lumefantrine in Healthy Adult Subjects.

Green JA, Mohamed K, Goyal N, Bouhired S, Hussaini A, Jones SW, Koh GC, Kostov I, Taylor M, Wolstenholm A, Duparc S. Green JA, et al. Antimicrob Agents Chemother. 2016 Nov 21;60(12):7321-7332. doi: 10.1128/AAC.01588-16. Print 2016 Dec. Antimicrob Agents Chemother. 2016. PMID: 27697758 Free PMC article. Clinical Trial.

6

A pharmacometrics approach to assess the feasibility of capillary microsampling to replace venous sampling in clinical studies: Tafenoquine case study.

Bachhav SS, Taylor M, Martin A, Green JA, Duparc S, Rolfe K, Sharma H, Tan LK, Goyal N. Bachhav SS, et al. Br J Clin Pharmacol. 2023 Mar;89(3):1187-1197. doi: 10.1111/bcp.15554. Epub 2022 Nov 9. Br J Clin Pharmacol. 2023. PMID: 36199201 Free article.

7

A novel metric to assess the clinical utility of a drug in the presence of efficacy and dropout information.

Goyal N, Gomeni R. Goyal N, et al. Clin Pharmacol Ther. 2012 Feb;91(2):215-9. doi: 10.1038/clpt.2011.197. Epub 2011 Nov 16. Clin Pharmacol Ther. 2012. PMID: 22089266

8

Exposure-Response Analyses for Tafenoquine after Administration to Patients with Plasmodium vivax Malaria.

Tenero D, Green JA, Goyal N. Tenero D, et al. Antimicrob Agents Chemother. 2015 Oct;59(10):6188-94. doi: 10.1128/AAC.00718-15. Epub 2015 Jul 27. Antimicrob Agents Chemother. 2015. PMID: 26248362 Free PMC article. Clinical Trial.

9

Application of the Stable Isotope Label Approach in Clinical Development-Supporting Dissolution Specifications for a Commercial Tablet Product with Tafenoquine, a Long Half-life Compound.

Goyal N, Mohamed K, Rolfe K, Sahota S, Ernest T, Duparc S, Taylor M, Casillas L, Koh GCKW. Goyal N, et al. AAPS J. 2018 Jun 4;20(4):74. doi: 10.1208/s12248-018-0234-5. AAPS J. 2018. PMID: 29869298 Clinical Trial.

10

Population Pharmacokinetics of Tafenoquine, a Novel Antimalarial.

Thakkar N, Green JA, Koh GCKW, Duparc S, Tenero D, Goyal N. Thakkar N, et al. Antimicrob Agents Chemother. 2018 Oct 24;62(11):e00711-18. doi: 10.1128/AAC.00711-18. Print 2018 Nov. Antimicrob Agents Chemother. 2018. PMID: 30201820 Free PMC article.

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