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Normal human CD4(+) helper T cells express Kv1.1 voltage-gated K(+) channels, and selective Kv1.1 block in T cells induces by itself robust TNFα production and secretion and activation of the NFκB non-canonical pathway.
Fellerhoff-Losch B, Korol SV, Ganor Y, Gu S, Cooper I, Eilam R, Besser M, Goldfinger M, Chowers Y, Wank R, Birnir B, Levite M. Fellerhoff-Losch B, et al. Among authors: korol sv. J Neural Transm (Vienna). 2016 Mar;123(3):137-57. doi: 10.1007/s00702-015-1446-9. Epub 2015 Nov 26. J Neural Transm (Vienna). 2016. PMID: 26611796
AMPA, NMDA and kainate glutamate receptor subunits are expressed in human peripheral blood mononuclear cells (PBMCs) where the expression of GluK4 is altered by pregnancy and GluN2D by depression in pregnant women.
Bhandage AK, Jin Z, Hellgren C, Korol SV, Nowak K, Williamsson L, Sundström-Poromaa I, Birnir B. Bhandage AK, et al. Among authors: korol sv. J Neuroimmunol. 2017 Apr 15;305:51-58. doi: 10.1016/j.jneuroim.2017.01.013. Epub 2017 Jan 21. J Neuroimmunol. 2017. PMID: 28284346
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