Nishitoh H - Search Results

1

The ASK1-specific inhibitors K811 and K812 prolong survival in a mouse model of amyotrophic lateral sclerosis.

Fujisawa T, Takahashi M, Tsukamoto Y, Yamaguchi N, Nakoji M, Endo M, Kodaira H, Hayashi Y, Nishitoh H, Naguro I, Homma K, Ichijo H. Fujisawa T, et al. Among authors: nishitoh h. Hum Mol Genet. 2016 Jan 15;25(2):245-53. doi: 10.1093/hmg/ddv467. Epub 2015 Nov 24. Hum Mol Genet. 2016. PMID: 26604152

2

Identification of important regions in the cytoplasmic juxtamembrane domain of type I receptor that separate signaling pathways of transforming growth factor-beta.

Saitoh M, Nishitoh H, Amagasa T, Miyazono K, Takagi M, Ichijo H. Saitoh M, et al. Among authors: nishitoh h. J Biol Chem. 1996 Feb 2;271(5):2769-75. doi: 10.1074/jbc.271.5.2769. J Biol Chem. 1996. PMID: 8576253 Free article.

3

Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1.

Saitoh M, Nishitoh H, Fujii M, Takeda K, Tobiume K, Sawada Y, Kawabata M, Miyazono K, Ichijo H. Saitoh M, et al. Among authors: nishitoh h. EMBO J. 1998 May 1;17(9):2596-606. doi: 10.1093/emboj/17.9.2596. EMBO J. 1998. PMID: 9564042 Free PMC article.

4

Activation of apoptosis signal-regulating kinase 1 (ASK1) by the adapter protein Daxx.

Chang HY, Nishitoh H, Yang X, Ichijo H, Baltimore D. Chang HY, et al. Among authors: nishitoh h. Science. 1998 Sep 18;281(5384):1860-3. doi: 10.1126/science.281.5384.1860. Science. 1998. PMID: 9743501

5

ASK1 is essential for JNK/SAPK activation by TRAF2.

Nishitoh H, Saitoh M, Mochida Y, Takeda K, Nakano H, Rothe M, Miyazono K, Ichijo H. Nishitoh H, et al. Mol Cell. 1998 Sep;2(3):389-95. doi: 10.1016/s1097-2765(00)80283-x. Mol Cell. 1998. PMID: 9774977 Free article.

6

Activation of apoptosis signal-regulating kinase 1 (ASK1) by tumor necrosis factor receptor-associated factor 2 requires prior dissociation of the ASK1 inhibitor thioredoxin.

Liu H, Nishitoh H, Ichijo H, Kyriakis JM. Liu H, et al. Among authors: nishitoh h. Mol Cell Biol. 2000 Mar;20(6):2198-208. doi: 10.1128/MCB.20.6.2198-2208.2000. Mol Cell Biol. 2000. PMID: 10688666 Free PMC article.

7

Apoptosis signal-regulating kinase 1 (ASK1) induces neuronal differentiation and survival of PC12 cells.

Takeda K, Hatai T, Hamazaki TS, Nishitoh H, Saitoh M, Ichijo H. Takeda K, et al. Among authors: nishitoh h. J Biol Chem. 2000 Mar 31;275(13):9805-13. doi: 10.1074/jbc.275.13.9805. J Biol Chem. 2000. PMID: 10734135 Free article.

8

ASK1 inhibits interleukin-1-induced NF-kappa B activity through disruption of TRAF6-TAK1 interaction.

Mochida Y, Takeda K, Saitoh M, Nishitoh H, Amagasa T, Ninomiya-Tsuji J, Matsumoto K, Ichijo H. Mochida Y, et al. Among authors: nishitoh h. J Biol Chem. 2000 Oct 20;275(42):32747-52. doi: 10.1074/jbc.M003042200. J Biol Chem. 2000. PMID: 10921914 Free article.

9

ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis.

Tobiume K, Matsuzawa A, Takahashi T, Nishitoh H, Morita K, Takeda K, Minowa O, Miyazono K, Noda T, Ichijo H. Tobiume K, et al. Among authors: nishitoh h. EMBO Rep. 2001 Mar;2(3):222-8. doi: 10.1093/embo-reports/kve046. EMBO Rep. 2001. PMID: 11266364 Free PMC article.

10

Tumor growth inhibition by arsenic trioxide (As2O3) in the orthotopic metastasis model of androgen-independent prostate cancer.

Maeda H, Hori S, Nishitoh H, Ichijo H, Ogawa O, Kakehi Y, Kakizuka A. Maeda H, et al. Among authors: nishitoh h. Cancer Res. 2001 Jul 15;61(14):5432-40. Cancer Res. 2001. PMID: 11454688

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