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Progress in the development of a recombinant vaccine for human hookworm disease: the Human Hookworm Vaccine Initiative.
Hotez PJ, Zhan B, Bethony JM, Loukas A, Williamson A, Goud GN, Hawdon JM, Dobardzic A, Dobardzic R, Ghosh K, Bottazzi ME, Mendez S, Zook B, Wang Y, Liu S, Essiet-Gibson I, Chung-Debose S, Xiao S, Knox D, Meagher M, Inan M, Correa-Oliveira R, Vilk P, Shepherd HR, Brandt W, Russell PK. Hotez PJ, et al. Int J Parasitol. 2003 Sep 30;33(11):1245-58. doi: 10.1016/s0020-7519(03)00158-9. Int J Parasitol. 2003. PMID: 13678639 Review.
Hookworm: "the great infection of mankind".
Hotez PJ, Bethony J, Bottazzi ME, Brooker S, Buss P. Hotez PJ, et al. PLoS Med. 2005 Mar;2(3):e67. doi: 10.1371/journal.pmed.0020067. Epub 2005 Mar 29. PLoS Med. 2005. PMID: 15783256 Free PMC article.
Antibodies against a secreted protein from hookworm larvae reduce the intensity of hookworm infection in humans and vaccinated laboratory animals.
Bethony J, Loukas A, Smout M, Brooker S, Mendez S, Plieskatt J, Goud G, Bottazzi ME, Zhan B, Wang Y, Williamson A, Lustigman S, Correa-Oliveira R, Xiao S, Hotez PJ. Bethony J, et al. Among authors: hotez pj. FASEB J. 2005 Oct;19(12):1743-5. doi: 10.1096/fj.05-3936fje. Epub 2005 Jul 21. FASEB J. 2005. PMID: 16037096
Expression of the Necator americanus hookworm larval antigen Na-ASP-2 in Pichia pastoris and purification of the recombinant protein for use in human clinical trials.
Goud GN, Bottazzi ME, Zhan B, Mendez S, Deumic V, Plieskatt J, Liu S, Wang Y, Bueno L, Fujiwara R, Samuel A, Ahn SY, Solanki M, Asojo OA, Wang J, Bethony JM, Loukas A, Roy M, Hotez PJ. Goud GN, et al. Among authors: hotez pj. Vaccine. 2005 Sep 15;23(39):4754-64. doi: 10.1016/j.vaccine.2005.04.040. Vaccine. 2005. PMID: 16054275
708 results