Protonation of lysine residues inverts cation/anion selectivity in a model channel.
Borisenko V, Sansom MS, Woolley GA.
Borisenko V, et al.
Biophys J. 2000 Mar;78(3):1335-48. doi: 10.1016/s0006-3495(00)76688-4.
Biophys J. 2000.
PMID: 10692320
Free PMC article.
A dimeric alamethicin analog with lysine at position 18 in the sequence (alm-K18) was previously shown to form stable anion-selective channels in membranes at pH 7.0 [Starostin, A. V., R. Butan, V. Borisenko, D. A. James, H. Wenschuh, M. S. Sansom, and G. A. …
A dimeric alamethicin analog with lysine at position 18 in the sequence (alm-K18) was previously shown to form stable anion-selective channe …