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Page 1
Site-selective protein conjugation at histidine.
Peciak K, Laurine E, Tommasi R, Choi JW, Brocchini S. Peciak K, et al. Among authors: tommasi r. Chem Sci. 2018 Oct 9;10(2):427-439. doi: 10.1039/c8sc03355b. eCollection 2019 Jan 14. Chem Sci. 2018. PMID: 30809337 Free PMC article.
Site-specific PEGylation at histidine tags.
Cong Y, Pawlisz E, Bryant P, Balan S, Laurine E, Tommasi R, Singh R, Dubey S, Peciak K, Bird M, Sivasankar A, Swierkosz J, Muroni M, Heidelberger S, Farys M, Khayrzad F, Edwards J, Badescu G, Hodgson I, Heise C, Somavarapu S, Liddell J, Powell K, Zloh M, Choi JW, Godwin A, Brocchini S. Cong Y, et al. Among authors: tommasi r. Bioconjug Chem. 2012 Feb 15;23(2):248-63. doi: 10.1021/bc200530x. Epub 2012 Feb 6. Bioconjug Chem. 2012. PMID: 22243664
In Vitro and In Vivo Evaluation of Cysteine Rebridged Trastuzumab-MMAE Antibody Drug Conjugates with Defined Drug-to-Antibody Ratios.
Bryant P, Pabst M, Badescu G, Bird M, McDowell W, Jamieson E, Swierkosz J, Jurlewicz K, Tommasi R, Henseleit K, Sheng X, Camper N, Manin A, Kozakowska K, Peciak K, Laurine E, Grygorash R, Kyle A, Morris D, Parekh V, Abhilash A, Choi JW, Edwards J, Frigerio M, Baker MP, Godwin A. Bryant P, et al. Among authors: tommasi r. Mol Pharm. 2015 Jun 1;12(6):1872-9. doi: 10.1021/acs.molpharmaceut.5b00116. Epub 2015 May 5. Mol Pharm. 2015. PMID: 25894424
Bridging disulfides for stable and defined antibody drug conjugates.
Badescu G, Bryant P, Bird M, Henseleit K, Swierkosz J, Parekh V, Tommasi R, Pawlisz E, Jurlewicz K, Farys M, Camper N, Sheng X, Fisher M, Grygorash R, Kyle A, Abhilash A, Frigerio M, Edwards J, Godwin A. Badescu G, et al. Among authors: tommasi r. Bioconjug Chem. 2014 Jun 18;25(6):1124-36. doi: 10.1021/bc500148x. Epub 2014 May 23. Bioconjug Chem. 2014. PMID: 24791606
74 results