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Interaction of the N-(3-Methylpyridin-2-yl)amide Derivatives of Flurbiprofen and Ibuprofen with FAAH: Enantiomeric Selectivity and Binding Mode.
Karlsson J, Morgillo CM, Deplano A, Smaldone G, Pedone E, Luque FJ, Svensson M, Novellino E, Congiu C, Onnis V, Catalanotti B, Fowler CJ. Karlsson J, et al. Among authors: novellino e. PLoS One. 2015 Nov 13;10(11):e0142711. doi: 10.1371/journal.pone.0142711. eCollection 2015. PLoS One. 2015. PMID: 26565710 Free PMC article.
Synthesis and pharmacological evaluation of potent and highly selective D3 receptor ligands: inhibition of cocaine-seeking behavior and the role of dopamine D3/D2 receptors.
Campiani G, Butini S, Trotta F, Fattorusso C, Catalanotti B, Aiello F, Gemma S, Nacci V, Novellino E, Stark JA, Cagnotto A, Fumagalli E, Carnovali F, Cervo L, Mennini T. Campiani G, et al. Among authors: novellino e. J Med Chem. 2003 Aug 28;46(18):3822-39. doi: 10.1021/jm0211220. J Med Chem. 2003. PMID: 12930145
Development of molecular probes for the identification of extra interaction sites in the mid-gorge and peripheral sites of butyrylcholinesterase (BuChE). Rational design of novel, selective, and highly potent BuChE inhibitors.
Campiani G, Fattorusso C, Butini S, Gaeta A, Agnusdei M, Gemma S, Persico M, Catalanotti B, Savini L, Nacci V, Novellino E, Holloway HW, Greig NH, Belinskaya T, Fedorko JM, Saxena A. Campiani G, et al. Among authors: novellino e. J Med Chem. 2005 Mar 24;48(6):1919-29. doi: 10.1021/jm049510k. J Med Chem. 2005. PMID: 15771436
Specific targeting highly conserved residues in the HIV-1 reverse transcriptase primer grip region. Design, synthesis, and biological evaluation of novel, potent, and broad spectrum NNRTIs with antiviral activity.
Fattorusso C, Gemma S, Butini S, Huleatt P, Catalanotti B, Persico M, De Angelis M, Fiorini I, Nacci V, Ramunno A, Rodriquez M, Greco G, Novellino E, Bergamini A, Marini S, Coletta M, Maga G, Spadari S, Campiani G. Fattorusso C, et al. Among authors: novellino e. J Med Chem. 2005 Nov 17;48(23):7153-65. doi: 10.1021/jm050257d. J Med Chem. 2005. PMID: 16279773
Development of piperazine-tethered heterodimers as potent antimalarials against chloroquine-resistant P. falciparum strains. Synthesis and molecular modeling.
Gemma S, Kukreja G, Campiani G, Butini S, Bernetti M, Joshi BP, Savini L, Basilico N, Taramelli D, Yardley V, Bertamino A, Novellino E, Persico M, Catalanotti B, Fattorusso C. Gemma S, et al. Among authors: novellino e. Bioorg Med Chem Lett. 2007 Jul 1;17(13):3535-9. doi: 10.1016/j.bmcl.2007.04.077. Epub 2007 Apr 29. Bioorg Med Chem Lett. 2007. PMID: 17493808
Exploiting protein fluctuations at the active-site gorge of human cholinesterases: further optimization of the design strategy to develop extremely potent inhibitors.
Butini S, Campiani G, Borriello M, Gemma S, Panico A, Persico M, Catalanotti B, Ros S, Brindisi M, Agnusdei M, Fiorini I, Nacci V, Novellino E, Belinskaya T, Saxena A, Fattorusso C. Butini S, et al. Among authors: novellino e. J Med Chem. 2008 Jun 12;51(11):3154-70. doi: 10.1021/jm701253t. Epub 2008 May 15. J Med Chem. 2008. PMID: 18479118
Novel propanamides as fatty acid amide hydrolase inhibitors.
Deplano A, Morgillo CM, Demurtas M, Björklund E, Cipriano M, Svensson M, Hashemian S, Smaldone G, Pedone E, Luque FJ, Cabiddu MG, Novellino E, Fowler CJ, Catalanotti B, Onnis V. Deplano A, et al. Among authors: novellino e. Eur J Med Chem. 2017 Aug 18;136:523-542. doi: 10.1016/j.ejmech.2017.05.033. Epub 2017 May 12. Eur J Med Chem. 2017. PMID: 28535469
747 results