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Endothelial NOTCH1 is suppressed by circulating lipids and antagonizes inflammation during atherosclerosis.
Briot A, Civelek M, Seki A, Hoi K, Mack JJ, Lee SD, Kim J, Hong C, Yu J, Fishbein GA, Vakili L, Fogelman AM, Fishbein MC, Lusis AJ, Tontonoz P, Navab M, Berliner JA, Iruela-Arispe ML. Briot A, et al. Among authors: tontonoz p. J Exp Med. 2015 Nov 16;212(12):2147-63. doi: 10.1084/jem.20150603. Epub 2015 Nov 9. J Exp Med. 2015. PMID: 26552708 Free PMC article.
Synthetic LXR ligand inhibits the development of atherosclerosis in mice.
Joseph SB, McKilligin E, Pei L, Watson MA, Collins AR, Laffitte BA, Chen M, Noh G, Goodman J, Hagger GN, Tran J, Tippin TK, Wang X, Lusis AJ, Hsueh WA, Law RE, Collins JL, Willson TM, Tontonoz P. Joseph SB, et al. Among authors: tontonoz p. Proc Natl Acad Sci U S A. 2002 May 28;99(11):7604-9. doi: 10.1073/pnas.112059299. Proc Natl Acad Sci U S A. 2002. PMID: 12032330 Free PMC article.
Identification of macrophage liver X receptors as inhibitors of atherosclerosis.
Tangirala RK, Bischoff ED, Joseph SB, Wagner BL, Walczak R, Laffitte BA, Daige CL, Thomas D, Heyman RA, Mangelsdorf DJ, Wang X, Lusis AJ, Tontonoz P, Schulman IG. Tangirala RK, et al. Among authors: tontonoz p. Proc Natl Acad Sci U S A. 2002 Sep 3;99(18):11896-901. doi: 10.1073/pnas.182199799. Epub 2002 Aug 22. Proc Natl Acad Sci U S A. 2002. PMID: 12193651 Free PMC article.
273 results