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SWI/SNF-mutant cancers depend on catalytic and non-catalytic activity of EZH2.
Kim KH, Kim W, Howard TP, Vazquez F, Tsherniak A, Wu JN, Wang W, Haswell JR, Walensky LD, Hahn WC, Orkin SH, Roberts CW. Kim KH, et al. Among authors: orkin sh. Nat Med. 2015 Dec;21(12):1491-6. doi: 10.1038/nm.3968. Epub 2015 Nov 9. Nat Med. 2015. PMID: 26552009 Free PMC article.
The SWI/SNF complex--chromatin and cancer.
Roberts CW, Orkin SH. Roberts CW, et al. Among authors: orkin sh. Nat Rev Cancer. 2004 Feb;4(2):133-42. doi: 10.1038/nrc1273. Nat Rev Cancer. 2004. PMID: 14964309 Review. No abstract available.
Epigenetic memory in induced pluripotent stem cells.
Kim K, Doi A, Wen B, Ng K, Zhao R, Cahan P, Kim J, Aryee MJ, Ji H, Ehrlich LI, Yabuuchi A, Takeuchi A, Cunniff KC, Hongguang H, McKinney-Freeman S, Naveiras O, Yoon TJ, Irizarry RA, Jung N, Seita J, Hanna J, Murakami P, Jaenisch R, Weissleder R, Orkin SH, Weissman IL, Feinberg AP, Daley GQ. Kim K, et al. Among authors: orkin sh. Nature. 2010 Sep 16;467(7313):285-90. doi: 10.1038/nature09342. Nature. 2010. PMID: 20644535 Free PMC article.
658 results