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FOXP3 and RORγt: transcriptional regulation of Treg and Th17.
Chen Z, Lin F, Gao Y, Li Z, Zhang J, Xing Y, Deng Z, Yao Z, Tsun A, Li B. Chen Z, et al. Among authors: gao y. Int Immunopharmacol. 2011 May;11(5):536-42. doi: 10.1016/j.intimp.2010.11.008. Epub 2010 Nov 23. Int Immunopharmacol. 2011. PMID: 21081189 Review.
The ubiquitin ligase Stub1 negatively modulates regulatory T cell suppressive activity by promoting degradation of the transcription factor Foxp3.
Chen Z, Barbi J, Bu S, Yang HY, Li Z, Gao Y, Jinasena D, Fu J, Lin F, Chen C, Zhang J, Yu N, Li X, Shan Z, Nie J, Gao Z, Tian H, Li Y, Yao Z, Zheng Y, Park BV, Pan Z, Zhang J, Dang E, Li Z, Wang H, Luo W, Li L, Semenza GL, Zheng SG, Loser K, Tsun A, Greene MI, Pardoll DM, Pan F, Li B. Chen Z, et al. Among authors: gao z, gao y. Immunity. 2013 Aug 22;39(2):272-85. doi: 10.1016/j.immuni.2013.08.006. Immunity. 2013. PMID: 23973223 Free PMC article.
USP22 is a positive regulator of NFATc2 on promoting IL2 expression.
Gao Y, Lin F, Xu P, Nie J, Chen Z, Su J, Tang J, Wu Q, Li Y, Guo Z, Gao Z, Li D, Shen J, Ge S, Tsun A, Li B. Gao Y, et al. Among authors: gao z. FEBS Lett. 2014 Mar 18;588(6):878-83. doi: 10.1016/j.febslet.2014.02.016. Epub 2014 Feb 20. FEBS Lett. 2014. PMID: 24561192 Free article.
Inflammation negatively regulates FOXP3 and regulatory T-cell function via DBC1.
Gao Y, Tang J, Chen W, Li Q, Nie J, Lin F, Wu Q, Chen Z, Gao Z, Fan H, Tsun A, Shen J, Chen G, Liu Z, Lou Z, Olsen NJ, Zheng SG, Li B. Gao Y, et al. Among authors: gao z. Proc Natl Acad Sci U S A. 2015 Jun 23;112(25):E3246-54. doi: 10.1073/pnas.1421463112. Epub 2015 Jun 9. Proc Natl Acad Sci U S A. 2015. PMID: 26060310 Free PMC article.
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