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Accelerated cardiac remodeling in desmoplakin transgenic mice in response to endurance exercise is associated with perturbed Wnt/β-catenin signaling.
Martherus R, Jain R, Takagi K, Mendsaikhan U, Turdi S, Osinska H, James JF, Kramer K, Purevjav E, Towbin JA. Martherus R, et al. Among authors: james jf. Am J Physiol Heart Circ Physiol. 2016 Jan 15;310(2):H174-87. doi: 10.1152/ajpheart.00295.2015. Epub 2015 Nov 6. Am J Physiol Heart Circ Physiol. 2016. PMID: 26545710 Free PMC article.
Disturbance in Z-disk mechanosensitive proteins induced by a persistent mutant myopalladin causes familial restrictive cardiomyopathy.
Huby AC, Mendsaikhan U, Takagi K, Martherus R, Wansapura J, Gong N, Osinska H, James JF, Kramer K, Saito K, Robbins J, Khuchua Z, Towbin JA, Purevjav E. Huby AC, et al. Among authors: james jf. J Am Coll Cardiol. 2014 Dec 30;64(25):2765-76. doi: 10.1016/j.jacc.2014.09.071. J Am Coll Cardiol. 2014. PMID: 25541130 Free PMC article.
Cardiac-specific VLCAD deficiency induces dilated cardiomyopathy and cold intolerance.
Xiong D, He H, James J, Tokunaga C, Powers C, Huang Y, Osinska H, Towbin JA, Purevjav E, Balschi JA, Javadov S, McGowan FX Jr, Strauss AW, Khuchua Z. Xiong D, et al. Am J Physiol Heart Circ Physiol. 2014 Feb;306(3):H326-38. doi: 10.1152/ajpheart.00931.2012. Epub 2013 Nov 27. Am J Physiol Heart Circ Physiol. 2014. PMID: 24285112 Free PMC article.
Altered regional cardiac wall mechanics are associated with differential cardiomyocyte calcium handling due to nebulette mutations in preclinical inherited dilated cardiomyopathy.
Maiellaro-Rafferty K, Wansapura JP, Mendsaikhan U, Osinska H, James JF, Taylor MD, Robbins J, Kranias EG, Towbin JA, Purevjav E. Maiellaro-Rafferty K, et al. Among authors: james jf. J Mol Cell Cardiol. 2013 Jul;60:151-60. doi: 10.1016/j.yjmcc.2013.04.021. Epub 2013 Apr 28. J Mol Cell Cardiol. 2013. PMID: 23632046 Free PMC article.
Sickle cell anemia mice develop a unique cardiomyopathy with restrictive physiology.
Bakeer N, James J, Roy S, Wansapura J, Shanmukhappa SK, Lorenz JN, Osinska H, Backer K, Huby AC, Shrestha A, Niss O, Fleck R, Quinn CT, Taylor MD, Purevjav E, Aronow BJ, Towbin JA, Malik P. Bakeer N, et al. Proc Natl Acad Sci U S A. 2016 Aug 30;113(35):E5182-91. doi: 10.1073/pnas.1600311113. Epub 2016 Aug 8. Proc Natl Acad Sci U S A. 2016. PMID: 27503873 Free PMC article.
124 results