Maehr R - Search Results

1

Controlling transcription in human pluripotent stem cells using CRISPR-effectors.

Genga RM, Kearns NA, Maehr R. Genga RM, et al. Among authors: maehr r. Methods. 2016 May 15;101:36-42. doi: 10.1016/j.ymeth.2015.10.014. Epub 2015 Oct 23. Methods. 2016. PMID: 26525193 Free PMC article. Review.

2

Generation of organized anterior foregut epithelia from pluripotent stem cells using small molecules.

Kearns NA, Genga RM, Ziller M, Kapinas K, Peters H, Brehm MA, Meissner A, Maehr R. Kearns NA, et al. Among authors: maehr r. Stem Cell Res. 2013 Nov;11(3):1003-12. doi: 10.1016/j.scr.2013.06.007. Epub 2013 Jun 29. Stem Cell Res. 2013. PMID: 23917481 Free article.

3

Cas9 effector-mediated regulation of transcription and differentiation in human pluripotent stem cells.

Kearns NA, Genga RM, Enuameh MS, Garber M, Wolfe SA, Maehr R. Kearns NA, et al. Among authors: maehr r. Development. 2014 Jan;141(1):219-23. doi: 10.1242/dev.103341. Development. 2014. PMID: 24346702 Free PMC article.

4

Functional annotation of native enhancers with a Cas9-histone demethylase fusion.

Kearns NA, Pham H, Tabak B, Genga RM, Silverstein NJ, Garber M, Maehr R. Kearns NA, et al. Among authors: maehr r. Nat Methods. 2015 May;12(5):401-403. doi: 10.1038/nmeth.3325. Epub 2015 Mar 16. Nat Methods. 2015. PMID: 25775043 Free PMC article.

5

Transcriptional Regulation with CRISPR/Cas9 Effectors in Mammalian Cells.

Pham H, Kearns NA, Maehr R. Pham H, et al. Among authors: maehr r. Methods Mol Biol. 2016;1358:43-57. doi: 10.1007/978-1-4939-3067-8_3. Methods Mol Biol. 2016. PMID: 26463376

6

Using an Inducible CRISPR-dCas9-KRAB Effector System to Dissect Transcriptional Regulation in Human Embryonic Stem Cells.

Parsi KM, Hennessy E, Kearns N, Maehr R. Parsi KM, et al. Among authors: maehr r. Methods Mol Biol. 2017;1507:221-233. doi: 10.1007/978-1-4939-6518-2_16. Methods Mol Biol. 2017. PMID: 27832543

7

A Single-Cell Transcriptomic Atlas of Thymus Organogenesis Resolves Cell Types and Developmental Maturation.

Kernfeld EM, Genga RMJ, Neherin K, Magaletta ME, Xu P, Maehr R. Kernfeld EM, et al. Among authors: maehr r. Immunity. 2018 Jun 19;48(6):1258-1270.e6. doi: 10.1016/j.immuni.2018.04.015. Epub 2018 Jun 5. Immunity. 2018. PMID: 29884461 Free PMC article.

8

Inferring population dynamics from single-cell RNA-sequencing time series data.

Fischer DS, Fiedler AK, Kernfeld EM, Genga RMJ, Bastidas-Ponce A, Bakhti M, Lickert H, Hasenauer J, Maehr R, Theis FJ. Fischer DS, et al. Among authors: maehr r. Nat Biotechnol. 2019 Apr;37(4):461-468. doi: 10.1038/s41587-019-0088-0. Epub 2019 Apr 1. Nat Biotechnol. 2019. PMID: 30936567 Free PMC article.

9

Single-Cell RNA-Sequencing-Based CRISPRi Screening Resolves Molecular Drivers of Early Human Endoderm Development.

Genga RMJ, Kernfeld EM, Parsi KM, Parsons TJ, Ziller MJ, Maehr R. Genga RMJ, et al. Among authors: maehr r. Cell Rep. 2019 Apr 16;27(3):708-718.e10. doi: 10.1016/j.celrep.2019.03.076. Cell Rep. 2019. PMID: 30995470 Free PMC article.

10

Diverse repertoire of human adipocyte subtypes develops from transcriptionally distinct mesenchymal progenitor cells.

Min SY, Desai A, Yang Z, Sharma A, DeSouza T, Genga RMJ, Kucukural A, Lifshitz LM, Nielsen S, Scheele C, Maehr R, Garber M, Corvera S. Min SY, et al. Among authors: maehr r. Proc Natl Acad Sci U S A. 2019 Sep 3;116(36):17970-17979. doi: 10.1073/pnas.1906512116. Epub 2019 Aug 16. Proc Natl Acad Sci U S A. 2019. PMID: 31420514 Free PMC article.

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