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Transcription factor Nr4a1 couples sympathetic and inflammatory cues in CNS-recruited macrophages to limit neuroinflammation.
Shaked I, Hanna RN, Shaked H, Chodaczek G, Nowyhed HN, Tweet G, Tacke R, Basat AB, Mikulski Z, Togher S, Miller J, Blatchley A, Salek-Ardakani S, Darvas M, Kaikkonen MU, Thomas GD, Lai-Wing-Sun S, Rezk A, Bar-Or A, Glass CK, Bandukwala H, Hedrick CC. Shaked I, et al. Among authors: kaikkonen mu. Nat Immunol. 2015 Dec;16(12):1228-34. doi: 10.1038/ni.3321. Epub 2015 Nov 2. Nat Immunol. 2015. PMID: 26523867 Free PMC article.
Colchicine promotes atherosclerotic plaque stability independently of inflammation.
Li W, Lin A, Hutton M, Dhaliwal H, Nadel J, Rodor J, Tumanov S, Örd T, Hadden M, Mokry M, Mol BM, Pasterkamp G, Padula MP, Geczy CL, Ramaswamy Y, Sluimer JC, Kaikkonen MU, Stocker R, Baker AH, Fisher EA, Patel S, Misra A. Li W, et al. Among authors: kaikkonen mu. bioRxiv [Preprint]. 2023 Oct 3:2023.10.03.560632. doi: 10.1101/2023.10.03.560632. bioRxiv. 2023. PMID: 37873248 Free PMC article. Preprint.
Cross-tissue omics analysis discovers ten adipose genes encoding secreted proteins in obesity-related non-alcoholic fatty liver disease.
Darci-Maher N, Alvarez M, Arasu UT, Selvarajan I, Lee SHT, Pan DZ, Miao Z, Das SS, Kaminska D, Örd T, Benhammou JN, Wabitsch M, Pisegna JR, Männistö V, Pietiläinen KH, Laakso M, Sinsheimer JS, Kaikkonen MU, Pihlajamäki J, Pajukanta P. Darci-Maher N, et al. Among authors: kaikkonen mu. EBioMedicine. 2023 Jun;92:104620. doi: 10.1016/j.ebiom.2023.104620. Epub 2023 May 22. EBioMedicine. 2023. PMID: 37224770 Free PMC article.
Secreted protein profiling of human aortic smooth muscle cells identifies vascular disease associations.
Aherrahrou R, Baig F, Theofilatos K, Lue D, Beele A, Örd T, Kaikkonen MU, Aherrahrou Z, Cheng Q, Ghosh S, Karnewar S, Karnewar V, Finn A, Owens GK, Joner M, Mayr M, Civelek M. Aherrahrou R, et al. Among authors: kaikkonen mu. medRxiv [Preprint]. 2023 Nov 10:2023.11.10.23298351. doi: 10.1101/2023.11.10.23298351. medRxiv. 2023. Update in: Arterioscler Thromb Vasc Biol. 2024 Apr;44(4):898-914. doi: 10.1161/ATVBAHA.123.320274 PMID: 37986932 Free PMC article. Updated. Preprint.
Genetic Regulation of SMC Gene Expression and Splicing Predict Causal CAD Genes.
Aherrahrou R, Lue D, Perry RN, Aberra YT, Khan MD, Soh JY, Örd T, Singha P, Yang Q, Gilani H, Benavente ED, Wong D, Hinkle J, Ma L, Sheynkman GM, den Ruijter HM, Miller CL, Björkegren JLM, Kaikkonen MU, Civelek M. Aherrahrou R, et al. Among authors: kaikkonen mu. Circ Res. 2023 Feb 3;132(3):323-338. doi: 10.1161/CIRCRESAHA.122.321586. Epub 2023 Jan 4. Circ Res. 2023. PMID: 36597873 Free PMC article.
Secreted Protein Profiling of Human Aortic Smooth Muscle Cells Identifies Vascular Disease Associations.
Aherrahrou R, Baig F, Theofilatos K, Lue D, Beele A, Örd T, Kaikkonen MU, Aherrahrou Z, Cheng Q, Ghosh SKB, Karnewar S, Karnewar V, Finn AV, Owens GK, Joner M, Mayr M, Civelek M. Aherrahrou R, et al. Among authors: kaikkonen mu. Arterioscler Thromb Vasc Biol. 2024 Apr;44(4):898-914. doi: 10.1161/ATVBAHA.123.320274. Epub 2024 Feb 8. Arterioscler Thromb Vasc Biol. 2024. PMID: 38328934
Mechanisms establishing TLR4-responsive activation states of inflammatory response genes.
Escoubet-Lozach L, Benner C, Kaikkonen MU, Lozach J, Heinz S, Spann NJ, Crotti A, Stender J, Ghisletti S, Reichart D, Cheng CS, Luna R, Ludka C, Sasik R, Garcia-Bassets I, Hoffmann A, Subramaniam S, Hardiman G, Rosenfeld MG, Glass CK. Escoubet-Lozach L, et al. Among authors: kaikkonen mu. PLoS Genet. 2011 Dec;7(12):e1002401. doi: 10.1371/journal.pgen.1002401. Epub 2011 Dec 8. PLoS Genet. 2011. PMID: 22174696 Free PMC article.
125 results