Mazer NA - Search Results

1

Evaluation of HDL-modulating interventions for cardiovascular risk reduction using a systems pharmacology approach.

Gadkar K, Lu J, Sahasranaman S, Davis J, Mazer NA, Ramanujan S. Gadkar K, et al. Among authors: mazer na. J Lipid Res. 2016 Jan;57(1):46-55. doi: 10.1194/jlr.M057943. Epub 2015 Nov 1. J Lipid Res. 2016. PMID: 26522778 Free PMC article.

2

A comparison of the theoretical relationship between HDL size and the ratio of HDL cholesterol to apolipoprotein A-I with experimental results from the Women's Health Study.

Mazer NA, Giulianini F, Paynter NP, Jordan P, Mora S. Mazer NA, et al. Clin Chem. 2013 Jun;59(6):949-58. doi: 10.1373/clinchem.2012.196949. Epub 2013 Feb 20. Clin Chem. 2013. PMID: 23426429 Free PMC article.

3

An in-silico model of lipoprotein metabolism and kinetics for the evaluation of targets and biomarkers in the reverse cholesterol transport pathway.

Lu J, Hübner K, Nanjee MN, Brinton EA, Mazer NA. Lu J, et al. Among authors: mazer na. PLoS Comput Biol. 2014 Mar 13;10(3):e1003509. doi: 10.1371/journal.pcbi.1003509. eCollection 2014 Mar. PLoS Comput Biol. 2014. PMID: 24625468 Free PMC article.

4

Analysis of "On/Off" Kinetics of a CETP Inhibitor Using a Mechanistic Model of Lipoprotein Metabolism and Kinetics.

Lu J, Cleary Y, Maugeais C, Kiu Weber CI, Mazer NA. Lu J, et al. Among authors: mazer na. CPT Pharmacometrics Syst Pharmacol. 2015 Aug;4(8):465-73. doi: 10.1002/psp4.27. Epub 2015 Apr 20. CPT Pharmacometrics Syst Pharmacol. 2015. PMID: 26380155 Free PMC article.

5

An in silico model of retinal cholesterol dynamics (RCD model): insights into the pathophysiology of dry AMD.

Zekavat SM, Lu J, Maugeais C, Mazer NA. Zekavat SM, et al. Among authors: mazer na. J Lipid Res. 2017 Jul;58(7):1325-1337. doi: 10.1194/jlr.M074088. Epub 2017 Apr 25. J Lipid Res. 2017. PMID: 28442497 Free PMC article.

6

Ocular Pharmacokinetics of Therapeutic Antibodies Given by Intravitreal Injection: Estimation of Retinal Permeabilities Using a 3-Compartment Semi-Mechanistic Model.

Hutton-Smith LA, Gaffney EA, Byrne HM, Maini PK, Gadkar K, Mazer NA. Hutton-Smith LA, et al. Among authors: mazer na. Mol Pharm. 2017 Aug 7;14(8):2690-2696. doi: 10.1021/acs.molpharmaceut.7b00164. Epub 2017 Jul 3. Mol Pharm. 2017. PMID: 28631484

7

Mathematical model of biliary lipid secretion: a quantitative analysis of physiological and biochemical data from man and other species.

Mazer NA, Carey MC. Mazer NA, et al. J Lipid Res. 1984 Sep;25(9):932-53. J Lipid Res. 1984. PMID: 6491540 Free article.

8

Ocular Half-Life of Intravitreal Biologics in Humans and Other Species: Meta-Analysis and Model-Based Prediction.

Caruso A, Füth M, Alvarez-Sánchez R, Belli S, Diack C, Maass KF, Schwab D, Kettenberger H, Mazer NA. Caruso A, et al. Among authors: mazer na. Mol Pharm. 2020 Feb 3;17(2):695-709. doi: 10.1021/acs.molpharmaceut.9b01191. Epub 2020 Jan 16. Mol Pharm. 2020. PMID: 31876425

9

Development of a quantitative semi-mechanistic model of Alzheimer's disease based on the amyloid/tau/neurodegeneration framework (the Q-ATN model).

Mazer NA, Hofmann C, Lott D, Gieschke R, Klein G, Boess F, Grimm HP, Kerchner GA, Baudler-Klein M, Smith J, Doody RS; Alzheimer's Disease Neuroimaging Initiative. Mazer NA, et al. Alzheimers Dement. 2023 Jun;19(6):2287-2297. doi: 10.1002/alz.12877. Epub 2022 Dec 1. Alzheimers Dement. 2023. PMID: 36454709

10

Theoretical Insights into the Retinal Dynamics of Vascular Endothelial Growth Factor in Patients Treated with Ranibizumab, Based on an Ocular Pharmacokinetic/Pharmacodynamic Model.

Hutton-Smith LA, Gaffney EA, Byrne HM, Caruso A, Maini PK, Mazer NA. Hutton-Smith LA, et al. Among authors: mazer na. Mol Pharm. 2018 Jul 2;15(7):2770-2784. doi: 10.1021/acs.molpharmaceut.8b00280. Epub 2018 May 29. Mol Pharm. 2018. PMID: 29734810

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